1916    The Chicago Cubs play their first game at Weeghman Park (currently Wrigley Field), defeating the Cincinnati Reds 7-6 in 11 innings

1919    Black Sox scandal: The Cincinnati Reds win the World Series.

1935    The first night game in Major League Baseball history is played in Cincinnati, Ohio, with the Cincinnati Reds beating the Philadelphia Phillies 2-1 at Crosley Field.

1939    The first Major League Baseball game is telecast, a doubleheader between the Cincinnati Reds and the Brooklyn Dodgers at Ebbets Field, in Brooklyn, New York.

1944    In baseball, 15-year old Joe Nuxhall of the Cincinnati Reds becomes the youngest player ever in a major-league game.

1975    Game 6 of the World Series is played between the Boston Red Sox and Cincinnati Reds. The game would be won on a home run off the left field foul pole at Fenway Park hit by Carlton Fisk in the bottom of the 12th inning, ending perhaps the greatest baseball game played in World Series history.

1989    Cincinnati Reds manager Pete Rose is banned from baseball for gambling by Commissioner A. Bartlett Giamatti.