Acropachy
Encyclopedia
Acropachy is a medical
condition characterized by subperiosteal new bone
formation, (aka Marie's Disease). This most commonly manifests as clubbing of the fingers and toes with soft tissue swelling. It is sometimes associated with Graves' disease
but not with other causes of hyperthyroidism. There is no effective treatment for acropachy.
Thyroid acropachy is an extreme manifestation of autoimmune thyroid disease. It presents with digital clubbing, swelling of digits and toes, and periosteal reaction of extremity bones. It is often associated with ophthalmopathy and thyroid dermopathy.
Hereditary acropachy (also known as "isolated congenital nail clubbing") may be associated with HPGD
.
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
condition characterized by subperiosteal new bone
Bone
Bones are rigid organs that constitute part of the endoskeleton of vertebrates. They support, and protect the various organs of the body, produce red and white blood cells and store minerals. Bone tissue is a type of dense connective tissue...
formation, (aka Marie's Disease). This most commonly manifests as clubbing of the fingers and toes with soft tissue swelling. It is sometimes associated with Graves' disease
Graves' disease
Graves' disease is an autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones...
but not with other causes of hyperthyroidism. There is no effective treatment for acropachy.
Thyroid acropachy is an extreme manifestation of autoimmune thyroid disease. It presents with digital clubbing, swelling of digits and toes, and periosteal reaction of extremity bones. It is often associated with ophthalmopathy and thyroid dermopathy.
Hereditary acropachy (also known as "isolated congenital nail clubbing") may be associated with HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase [NAD+] is an enzyme that in humans is encoded by the HPGD gene.In melanocytic cells HPGD gene expression may be regulated by MITF.-Further reading:...
.