Inositol pentakisphosphate
Encyclopedia
Inositol pentakisphosphate (abbreviated IP5) is a molecule derived from inositol tetrakisphosphate by adding a phosphate group with the help of inositol polyphosphate multikinase (IPMK). It is believed to be one of the many second messengers in the inositol phosphate
family. It "is implicated in a wide array of biological and pathophysiological responses, including tumorigenesis, invasion and metastasis, therefore specific inhibitors of the kinase may prove useful in cancer therapy."
IP5 also plays a role in defense signaling in plants. It potentiates the interaction of the plant hormone JA-Ile
by its receptor.
Inositol phosphate
Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation.The group comprises:...
family. It "is implicated in a wide array of biological and pathophysiological responses, including tumorigenesis, invasion and metastasis, therefore specific inhibitors of the kinase may prove useful in cancer therapy."
IP5 also plays a role in defense signaling in plants. It potentiates the interaction of the plant hormone JA-Ile
Jasmonate
Jasmonate and its derivatives are lipid-based hormone signals that regulate a wide range of processes in plants, ranging from growth and photosynthesis to reproductive development. In particular, JAs are critical for plant defense against herbivory and plant responses to poor environmental...
by its receptor.