Sports

• James Hughes (rugby)
  James Hughes (rugby)
  James Charles Hughes was a rugby union player who represented Australia.Hughes, a flanker, was born in Sydney, New South Wales and claimed a total of 2 international rugby caps for Australia.-References:...
  
   (c. 1885–c. 1943), Australian rugby union player
• James Hughes (ice hockey)
  James Hughes (ice hockey)
  James Hughes is a retired Canadian professional ice hockey player who played 40 games in the National Hockey League for the Detroit Red Wings.-External links:...
  
   (1906–1983), Canadian professional ice hockey player
• Jay Hughes
  Jay Hughes
  James Jay Hughes was an American Major League Baseball pitcher, who played four seasons from to .Hughes was born in Sacramento, California...
  
   (1874–1924), also known as Jim Hughes, American Major League Baseball pitcher, who played four seasons from 1898 to 1902
• Jim Hughes (1950s pitcher) (1923–2001), American baseball pitcher
• Jim Hughes (1970s pitcher)
  Jim Hughes (1970s pitcher)
  James Michael Hughes is a former Major League Baseball pitcher. He pitched all or part of four seasons in the majors, from until , all with the Minnesota Twins.-External links:...
  
   (born 1951), American baseball pitcher
• James Hughes (boxer)
  James Hughes (boxer)
  James Melvin Hughes was professional boxer in the welterweight division.- Boxing career :Known as "Jesse James" and "The Outlaw", Hughes turned professional in 1987 and is perhaps best known for his appearances on the USA Tuesday Night Fights series...
  
   (1965–1995), American flyweight boxer
• Jimmy Hughes (footballer) (1909–1966), English footballer
• Jamie Hughes (born 1977), former professional English footballer

Politicians

• James Hughes (British politician) (died 1845), British Member of Parliament for Grantham
• James B. Hughes
  James B. Hughes
  -Early life and education:James was born October 12, 1805 in Prince Edward County, Virginia to Simon Hughes and Betsy Colman Bigger. He was raised just outside Farmville near Hampden-Sydney...
  
   (1805–1873), American newspaper publisher, state legislator for Ohio
• James Madison Hughes
  James Madison Hughes
  James Madison Hughes was a U.S. Representative from Missouri.Born in Bourbon County, Kentucky, Hughes received a liberal schooling.He studied law.He was admitted to the bar and practiced in Liberty, Missouri....
  
   (1809–1861), U.S. Representative from Missouri
• James Hughes (representative)
  James Hughes (representative)
  James Hughes was a United States Representative from Indiana. He was born in Baltimore County, Maryland. He attended the common schools and Indiana University at Bloomington, Indiana. He studied law, was admitted to the bar in 1842, and commenced practice in Indiana.Hughes served in the...
  
   (1823–1873), U.S. Representative from Indiana
• James Joseph Hughes
  James Joseph Hughes
  James Joseph Hughes was a Canadian politician.Born in St. Mary's Road, Prince Edward Island, Hughes was the son of Irish parents. He was educated at the Log School House in St. Mary's Road and was a graduate of St...
  
   (1856–1941), Canadian Senator and Member of Parliament
• James A. Hughes
  James A. Hughes
  James Anthony Hughes was a member of the United States House of Representatives from the state of West Virginia....
  
   (1861–1930), U.S. Representative from West Virginia
• James H. Hughes
  James H. Hughes
  James Hurd Hughes was an American lawyer and politician from Dover, in Kent County, Delaware. He was a member of the Democratic Party, who served as U.S. Senator from Delaware.-Early life and family:...
  
   (1867–1953), American lawyer and politician, U.S. Senator from Delaware
• James F. Hughes
  James F. Hughes
  James Frederic Hughes was a U.S. Representative from Wisconsin.Born in Green Bay, Wisconsin, Hughes graduated from West Green Bay High School in 1901. After moving to De Pere, Wisconsin in 1901, he was employed as a salesman. He was a member of the De Pere Board of Education...
  
   (1883–1940), U.S. Representative from Wisconsin
• James Hughes (Irish politician)
  James Hughes (Irish politician)
  James Hughes was an Irish Fine Gael politician. A farmer, he was first elected to Dáil Éireann as a Teachta Dála for the Carlow–Kildare constituency at the 1938 general election. He was re-elected at the 1943 and 1944 general elections. He died in 1948 during the course of the 12th Dáil, but no...
  
   (died 1948), Irish Fine Gael politician
• Jim Hughes (politician) (born 1964), Ohio politician

Others

• James Hughes (bishop) (1894–1979), Anglican bishop
• Jimmy Hughes (singer)
  Jimmy Hughes (singer)
  Jimmy Hughes is an American former rhythm and blues singer, whose biggest successes in the mid 1960s, notably his hit "Steal Away", were important in the early development of the Muscle Shoals music industry.-Life and career:...
  
   (born 1938), American soul singer
• Jimmy Hughes (musician)
  Jimmy Hughes (musician)
  James Hughes is an English bassist who has played with many punk rock and New Wave bands, and whose career as a rock musician and writer continues to this day....
  
   (born 1958), British punk rock/New Wave bassist
• James Hughes (sociologist), American sociologist and bioethicist
• James Howard Hughes (Educational technologist) (born 1958), Technolgy Pioneer and Computer Guru