Vascular endothelial growth factor C
Encyclopedia
Vascular endothelial growth factor C is a VEGF
. The human gene
encoding it is VEGFC.
is caused by an imbalance between lymphatic vessel formation and absorption. Experimentally this can be created by overexpression of VEGF-C
Lymphangioma
:
Overexpression of VEGF-C causes lymphatics to enlarge possibly facilitates metastasis.
Vascular endothelial growth factor
Vascular endothelial growth factor is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate....
. The human gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
encoding it is VEGFC.
Pathological VEGF-C Expression
LymphedemaLymphedema
Lymphedema , also known as lymphatic obstruction, is a condition of localized fluid retention and tissue swelling caused by a compromised lymphatic system....
is caused by an imbalance between lymphatic vessel formation and absorption. Experimentally this can be created by overexpression of VEGF-C
Lymphangioma
Lymphangioma
Lymphangiomas are malformations of the lymphatic system, which is the network of vessels responsible for returning to the venous system excess fluid from tissues. These malformations can occur at any age and may involve any part of the body, but 90% occur in children less than 2 years of age and...
:
Overexpression of VEGF-C causes lymphatics to enlarge possibly facilitates metastasis.