Villonodular synovitis
Encyclopedia
Villonodular synovitis is a type of synovial
swelling.
Types include:
Though they have very different names, they have the same histology, and stain positive for CD68
, HAM56, and vimentin
.
They are sometimes discussed together.
Synovial
Synovial may refer to:* Synovial fluid* Synovial joint* Synovial membrane...
swelling.
Types include:
- Pigmented villonodular synovitisPigmented villonodular synovitisPigmented villonodular synovitis is a joint disease characterized by inflammation and overgrowth of the joint lining. It usually affects the hip or knee. It can also occur in the shoulder, ankle, elbow, hand or foot. In PVNS the lining of the joint, called the synovium, becomes swollen and grows....
(PVNS) - Giant cell tumor of the tendon sheathGiant cell tumor of the tendon sheathGiant-cell tumor of the tendon sheath, also known as giant-cell synovioma and localized nodular tenosynovitis, is a firm lesion, measuring 1 to 3 cm in diameter, and is most commonly attached to the tendons of the fingers, hands, and wrists, with a predilection for the flexor surfaces...
(GCTS)
Though they have very different names, they have the same histology, and stain positive for CD68
CD68
CD68 is a glycoprotein which binds to low density lipoprotein.It is expressed on monocytes/macrophages.The mouse equivalent is called "macrosialin".-Use in pathology:...
, HAM56, and vimentin
Vimentin
Vimentin is a type III intermediate filament protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprise the cytoskeleton...
.
They are sometimes discussed together.