FD&C Orange Number 1
Encyclopedia
FD&C Orange Number 1 was one of the first water soluble dyes
Food coloring
Food coloring is a substance, liquid or powder, that is added to food or drink to change its color. Food coloring is used both in commercial food production and in domestic cooking...

 to be commercialized, and one of seven original food dyes allowed under the Pure Food and Drug Act
Pure Food and Drug Act
The Pure Food and Drug Act of June 30, 1906, is a United States federal law that provided federal inspection of meat products and forbade the manufacture, sale, or transportation of adulterated food products and poisonous patent medicines...

of June 30, 1906. In the early 1950s, after several cases were reported of sickness in children who had eaten foods with excessive amounts of dye, the FDA conducted new, more thorough and rigorous testing on food dyes. Orange 1 was outlawed for food use in 1956.
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