Graham C. Walker
Encyclopedia
Graham C. Walker is an American biologist, notable for his work explicating the structure and function of proteins involved in DNA repair
DNA repair
DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1...

 and mutagenesis
Mutagenesis
Mutagenesis is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be achieved experimentally using laboratory procedures...

, with applications for cancer, and for understanding rhizobium
Rhizobium
Rhizobium is a genus of Gram-negative soil bacteria that fix nitrogen. Rhizobium forms an endosymbiotic nitrogen fixing association with roots of legumes and Parasponia....

 (bacterial) functions that infect plants and mammals.

In addition to his scientific achievements, Walker is coordinating a program at MIT to develop curricular
Curriculum
See also Syllabus.In formal education, a curriculum is the set of courses, and their content, offered at a school or university. As an idea, curriculum stems from the Latin word for race course, referring to the course of deeds and experiences through which children grow to become mature adults...

 materials in biology.

Biography

Walker earned a B.Sc. degree from Carleton University
Carleton University
Carleton University is a comprehensive university located in the capital of Canada, Ottawa, Ontario. The enabling legislation is The Carleton University Act, 1952, S.O. 1952. Founded as a small college in 1942, Carleton now offers over 65 programs in a diverse range of disciplines. Carleton has...

, and his Ph.D. in 1974 from the University of Illinois. He did postdoctoral work at the University of Illinois and at University of California, Berkeley
University of California, Berkeley
The University of California, Berkeley , is a teaching and research university established in 1868 and located in Berkeley, California, USA...

.

He is currently a professor at MIT.

Notable publications

  • Errol C. Friedberg, Graham C. Walker, Wolfram Siede, and Richard D. Wood, DNA Repair and Mutagenesis (2005 edition of notable textbook)
  • Bradley T. Smith, Alan D. Grossman, and Graham C. Walker, "Visualization of Mismatch Repair in Bacterial Cells", Molecular Cell, v.8, pp. 1197–1206 (Dec. 2001)
  • LeVier, K., Phillips, R.W., Grippe, V.K., Roop II, R.M. and Walker, G.C. Similar requirements of a plant symbiont and a mammalian pathogen for prolonged intracellular survival. Science 287:2492-2493 (2000)
  • G. C. Walker, "Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escheriscia coli", Microbiological Reviews (full text available at PubMed Central)

Awards

  • 1970 - Woodrow Wilson National Fellow
  • 1978-1982 - Rita Allen Foundation Scholar
  • 1994 - Elected Fellow, American Academy of Microbiology
  • 2006 Environmental Mutagen Society Award
  • American Cancer Society
    American Cancer Society
    The American Cancer Society is the "nationwide community-based voluntary health organization" dedicated, in their own words, "to eliminating cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer, through research, education, advocacy, and...

    Research Professor
  • Charles Ross Scholar Award for Cancer Research
  • Arthur C. Smith Award
  • Stone Lectureship, Pennsylvania State University

Footnotes

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