I. Herbert Scheinberg
Encyclopedia
I. Herbert Scheinberg was a physician who specialized in Wilson's disease
Wilson's disease
Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease...

 and other rare hereditary diseases.

Scheinberg attended DeWitt Clinton High School
DeWitt Clinton High School
DeWitt Clinton High School is an American high school located in the Bronx, New York City, New York.-History:Clinton opened in 1897 at 60 West 13th Street at the northern end of Greenwich Village under the name of Boys High School, although this Boys High School was not related to the one in Brooklyn...

 in the Bronx
The Bronx
The Bronx is the northernmost of the five boroughs of New York City. It is also known as Bronx County, the last of the 62 counties of New York State to be incorporated...

, New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

. He won admission to Harvard University
Harvard University
Harvard University is a private Ivy League university located in Cambridge, Massachusetts, United States, established in 1636 by the Massachusetts legislature. Harvard is the oldest institution of higher learning in the United States and the first corporation chartered in the country...

, graduating with a bachelor's degree
Bachelor's degree
A bachelor's degree is usually an academic degree awarded for an undergraduate course or major that generally lasts for three or four years, but can range anywhere from two to six years depending on the region of the world...

 in chemistry
Chemistry
Chemistry is the science of matter, especially its chemical reactions, but also its composition, structure and properties. Chemistry is concerned with atoms and their interactions with other atoms, and particularly with the properties of chemical bonds....

 in 1940. He then attended Harvard Medical School
Harvard Medical School
Harvard Medical School is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts....

, graduating in 1943. He did his internship at Boston's Peter Bent Brigham Hospital, followed by a stint in the Army Medical Corps
Medical Corps (United States Army)
The Medical Corps of the U.S. Army is a staff corps of the U.S. Army Medical Department consisting of commissioned medical officers – physicians with either an MD or a DO degree, at least one year of post-graduate clinical training, and a state medical license.The MC traces its earliest origins...

.

Scheinberg began his academic career back at Harvard. He joined the Albert Einstein College of Medicine
Albert Einstein College of Medicine
Albert Einstein College of Medicine is a graduate school of Yeshiva University. It is a not-for-profit, private, nonsectarian medical school located on the Jack and Pearl Resnick Campus in the Morris Park neighborhood of the borough of the Bronx of New York City...

 upon its foundation in 1955.

Scheinberg and David Gitlin developed an inexpensive blood test to measure levels of ceruloplasmin
Ceruloplasmin
Ceruloplasmin is a ferroxidase enzyme that in humans is encoded by the CP gene.Ceruloplasmin is the major copper-carrying protein in the blood, and in addition plays a role in iron metabolism. It was first described in 1948...

 in the blood
Blood
Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells....

, making the diagnosis of Wilson's disease easier. A version of the test is still in use today.

While Scheinberg was a faculty member at Albert Einstein College of Medicine, Scheinberg, Irmin Sternlieb and John Walshe of Cambridge University researched the use of penicillamine
Penicillamine
Penicillamine is a pharmaceutical of the chelator class. It is sold under the trade names of Cuprimine and Depen. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic...

as a treatment for Wilson's Disease.
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