Kienbock's disease
Encyclopedia
Kienbock's disease is a disorder of the wrist
. It is named for Dr. Robert Kienböck
, a radiologist in Vienna, Austria who described osteomalacia
of the lunate in 1910.
It is breakdown of the lunate bone
, a carpal bone in the wrist
that articulates with the radius
in the forearm. Specifically, Kienbock's disease is another name for avascular necrosis
(death and fracture of bone tissue due to interruption of blood supply) with fragmentation and collapse of the lunate. This has classically been attributed to arterial disruption, but may also occur after events that produce venous congestion with elevated interosseous pressure.
Recent studies have made a correlation between Kienbock's sufferers and Western European ancestry, but no definitive link can be positively confirmed.
The necrosis of the lunate bone can frequently be traced to a trauma to the wrist, like a compound fracture, which could cause the lunate's blood supply to be interrupted. There has also been documentation showing that some people have only one artery supplying the lunate, which could be easily severed or pinched, even through a slight sprain, causing the patient to develop Kienbock's. Despite a preponderance of evidence, no particular etiology has been conclusively verified..'
Data exists on the internet that most people suffering from Kienbock's are affected in their dominant hand, though about one-third of sufferers report the condition in their non-dominant hand.
Kienbock's disease is classified as a "rare disorder," meaning that it affects fewer than 200,000 people in the U.S. population.
Many Kienbock's patients are frustrated by the lack of consensus among hand surgeons about optimal treatments for Kienbock's. No matter what the disease's stage of progression, there is no one best treatment, and the decision is often based partially, or even mostly, on incidental factors such as the patient's pain tolerance, the patient's desire to return to active use of the hand (such as in manual occupations), and the surgeon's level of expertise with different treatments.
Though, since each case of Kienbock's is different, the makeup of the wrist and arm bones are important factors which are individualized to each patient. Therefore, one surgery will never be able to solve all the problems associated with the disease. Thus, no consensus can be reached among surgeons.
Depending on what stage the disease is diagnosed in will depend on the best course of treatment. For example, if diagnosed in stage 2, a surgeon may recommend a Horry Procedure to attempt to replenish the blood supply to the lunate, and keep it from reaching stage 3.
Depending on the stage the disease is in when it is discovered, varying treatments are applied.
If X-rays show a mostly intact lunate (not having lost a great deal of size, and not having been compressed into a triangular shape), but an MRI shows a lack of blood flow to the bone, then revascularization
is normally attempted. Revascularization techniques, usually involving a bone graft taken elsewhere from the body — often held in place by an external fixator for a period of weeks or months — have been successful at stages as late as 3B, although their use at later stages (like most treatments for Kienbock's) is controversial.
Some Kienbock's patients present with an abnormally large difference in length between the radius and the ulna
, termed "ulnar variance", which is hypothesized to cause undue pressure on the lunate, contributing to its avascularity. In cases with such a difference, radial shortening is commonly performed. In this procedure, the radius (the inside long bone) is shortened by a given length, usually between 2 and 5 mm, to relieve the pressure on the dying lunate. A titanium plate is inserted to hold the newly shortened bone together.
During Stage 3, the lunate has begun to break apart due to the pressure of the surrounding bones. This causes sharp fragments of bone to float between the joints, causing excruciating pain. At this point, the lunate is ready for removal. The most frequently performed surgery is the Proximal Row Carpectomy, where the lunate, scaphoid and triquetrum are extracted. This greatly limits the range of motion of the wrist, but pain relief can be achieved for longer than after the other surgeries.
Another surgical option for this stage is a titanium or silicon implant that takes place of the lunate, though doctors shy from this due to a tendency of the implant to smooth the edges of the surrounding bones, thus causing painful pinched nerves when the bones slip out of place.
After the lunate is removed, another procedure, ulnar shortening can be performed. This relieves pressure on the newly formed wrist joint of the pisiform, hamate and capitate. Depending on the surgeon, the procedure may be performed the same way as the radial shortening where a small section is removed, or the entire top of the ulna may be excised.
At Stage 4, the lunate has completely disintegrated and the other bones in the wrist have radiated downward to fill in the void. The hand now has a deformed, crippled appearance. The only procedure that can be done is the total wrist fusion, where a plate is inserted on the top of the wrist from the radius to the carpals, effectively freezing all flexion and movement in the wrist. Rotation is still possible as it is controlled by the radius and ulna.
This is currently the last and most complete surgical option for Kienbock's sufferers.
Most of the treatments described here are not mutually exclusive — meaning that a single patient may receive many of them in his quest to relieve pain. For instance, some patients have had casting, bone graft, radial shortening, proximal row carpectomy, and wrist fusion, all on the same hand.
Wrist
In human anatomy, the wrist is variously defined as 1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand;...
. It is named for Dr. Robert Kienböck
Robert Kienböck
Robert Kienböck was an Austrian radiologist who was a native of Vienna.In 1895 he earned his medical doctorate at the University of Vienna, and spent the next year abroad. He returned to Vienna as an assistant to Leopold von Schrötter , a laryngologist, and began working in the new science of...
, a radiologist in Vienna, Austria who described osteomalacia
Osteomalacia
Osteomalacia is the softening of the bones caused by defective bone mineralization secondary to inadequate amounts of available phosphorus and calcium, or because of overactive resorption of calcium from the bone as a result of hyperparathyroidism...
of the lunate in 1910.
It is breakdown of the lunate bone
Lunate bone
The lunate bone is a carpal bone in the human hand that may be distinguished by its deep concavity and crescentic outline. It is situated in the center of the proximal row of the carpus region between the fore arm and hand...
, a carpal bone in the wrist
Wrist
In human anatomy, the wrist is variously defined as 1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand;...
that articulates with the radius
Radius (bone)
The radius is one of the two large bones of the forearm, the other being the ulna. It extends from the lateral side of the elbow to the thumb side of the wrist and runs parallel to the ulna, which exceeds it in length and size. It is a long bone, prism-shaped and slightly curved longitudinally...
in the forearm. Specifically, Kienbock's disease is another name for avascular necrosis
Avascular necrosis
Avascular necrosis is a disease where there is cellular death of bone components due to interruption of the blood supply. Without blood, the bone tissue dies and the bone collapses...
(death and fracture of bone tissue due to interruption of blood supply) with fragmentation and collapse of the lunate. This has classically been attributed to arterial disruption, but may also occur after events that produce venous congestion with elevated interosseous pressure.
Predisposing factors
The exact cause of Kienbock's is known, though there are thought to be a number of factors predisposing a person to Kienbock's.Recent studies have made a correlation between Kienbock's sufferers and Western European ancestry, but no definitive link can be positively confirmed.
The necrosis of the lunate bone can frequently be traced to a trauma to the wrist, like a compound fracture, which could cause the lunate's blood supply to be interrupted. There has also been documentation showing that some people have only one artery supplying the lunate, which could be easily severed or pinched, even through a slight sprain, causing the patient to develop Kienbock's. Despite a preponderance of evidence, no particular etiology has been conclusively verified..'
Data exists on the internet that most people suffering from Kienbock's are affected in their dominant hand, though about one-third of sufferers report the condition in their non-dominant hand.
Kienbock's disease is classified as a "rare disorder," meaning that it affects fewer than 200,000 people in the U.S. population.
Many Kienbock's patients are frustrated by the lack of consensus among hand surgeons about optimal treatments for Kienbock's. No matter what the disease's stage of progression, there is no one best treatment, and the decision is often based partially, or even mostly, on incidental factors such as the patient's pain tolerance, the patient's desire to return to active use of the hand (such as in manual occupations), and the surgeon's level of expertise with different treatments.
Though, since each case of Kienbock's is different, the makeup of the wrist and arm bones are important factors which are individualized to each patient. Therefore, one surgery will never be able to solve all the problems associated with the disease. Thus, no consensus can be reached among surgeons.
Classification scheme
Kienbock's disease is classified by features that indicate the severity of the problem.- Normal radiograph (possible lunate fracture).
- Sclerosis of the lunate without collapse. (Portions of the lunate begin to deteriorate. This shows as a white blemish on x-rays.)
- Lunate is completely dead. (The entire Lunate is dead. There is no living matter within the bone.)
- Changes up to and including fragmentation, with superimposed arthritic changes.
Depending on what stage the disease is diagnosed in will depend on the best course of treatment. For example, if diagnosed in stage 2, a surgeon may recommend a Horry Procedure to attempt to replenish the blood supply to the lunate, and keep it from reaching stage 3.
Treatment
Operations that attempt to restore a blood supply to the lunate may be performed.Depending on the stage the disease is in when it is discovered, varying treatments are applied.
If X-rays show a mostly intact lunate (not having lost a great deal of size, and not having been compressed into a triangular shape), but an MRI shows a lack of blood flow to the bone, then revascularization
Revascularization
Revascularization is "a surgical procedure for the provision of a new, additional, or augmented blood supply to a body part or organ." The term derives from the prefix re-, in this case meaning "restoration" and vasculature, which refers to the circulatory structures of an organ.Revascularization...
is normally attempted. Revascularization techniques, usually involving a bone graft taken elsewhere from the body — often held in place by an external fixator for a period of weeks or months — have been successful at stages as late as 3B, although their use at later stages (like most treatments for Kienbock's) is controversial.
Some Kienbock's patients present with an abnormally large difference in length between the radius and the ulna
Ulna
The ulna is one of the two long bones in the forearm, the other being the radius. It is prismatic in form and runs parallel to the radius, which is shorter and smaller. In anatomical position The ulna is one of the two long bones in the forearm, the other being the radius. It is prismatic in form...
, termed "ulnar variance", which is hypothesized to cause undue pressure on the lunate, contributing to its avascularity. In cases with such a difference, radial shortening is commonly performed. In this procedure, the radius (the inside long bone) is shortened by a given length, usually between 2 and 5 mm, to relieve the pressure on the dying lunate. A titanium plate is inserted to hold the newly shortened bone together.
During Stage 3, the lunate has begun to break apart due to the pressure of the surrounding bones. This causes sharp fragments of bone to float between the joints, causing excruciating pain. At this point, the lunate is ready for removal. The most frequently performed surgery is the Proximal Row Carpectomy, where the lunate, scaphoid and triquetrum are extracted. This greatly limits the range of motion of the wrist, but pain relief can be achieved for longer than after the other surgeries.
Another surgical option for this stage is a titanium or silicon implant that takes place of the lunate, though doctors shy from this due to a tendency of the implant to smooth the edges of the surrounding bones, thus causing painful pinched nerves when the bones slip out of place.
After the lunate is removed, another procedure, ulnar shortening can be performed. This relieves pressure on the newly formed wrist joint of the pisiform, hamate and capitate. Depending on the surgeon, the procedure may be performed the same way as the radial shortening where a small section is removed, or the entire top of the ulna may be excised.
At Stage 4, the lunate has completely disintegrated and the other bones in the wrist have radiated downward to fill in the void. The hand now has a deformed, crippled appearance. The only procedure that can be done is the total wrist fusion, where a plate is inserted on the top of the wrist from the radius to the carpals, effectively freezing all flexion and movement in the wrist. Rotation is still possible as it is controlled by the radius and ulna.
This is currently the last and most complete surgical option for Kienbock's sufferers.
Most of the treatments described here are not mutually exclusive — meaning that a single patient may receive many of them in his quest to relieve pain. For instance, some patients have had casting, bone graft, radial shortening, proximal row carpectomy, and wrist fusion, all on the same hand.