Nannina de' Medici, was born under the name Lucrezia (Florence, 14 February 1448 – 14 May 1493), and was the third daughter of Piero di Cosimo de' Medici

Piero di Cosimo de' Medici

Piero di Cosimo de' Medici , , was the de facto ruler of Florence from 1464 to 1469, during the Italian Renaissance. He was the father of Lorenzo the Magnificent and Giuliano de' Medici-Biography:Piero was born in Florence, the son of Cosimo de' Medici the Elder and Contessina de' Bardi...

 and Lucrezia Tornabuoni

Lucrezia Tornabuoni

Lucrezia Tornabuoni was a daughter of Francesco di Simone Tornabuoni and Nanna di Niccolo di Luigi Guicciardini. Her brother was Giovanni Tornabuoni.- Biography :...

. She is also known as Lucrezia di Piero de' Medici. She was the older sister of Lorenzo de' Medici

Lorenzo de' Medici

Lorenzo de' Medici was an Italian statesman and de facto ruler of the Florentine Republic during the Italian Renaissance. Known as Lorenzo the Magnificent by contemporary Florentines, he was a diplomat, politician and patron of scholars, artists and poets...

. Hers was a cultured and refined education, but more "filtered" than that of the siblings males Lorenzo and Giuliano.

Nannina was the family name of the great-grandmother Piccarda Bueri

Piccarda Bueri

Piccarda Bueri was an Italian noblewoman of the Renaissance.-Life:She was the daughter of Edward Bueri, a member of a family of ancient lineage from Florence with economic interests in other cities; the family was in fact in Verona in the first half of the fourteenth century when she was born...

. At least two portraits of her in youth are known to exist: One in the head of the Magi, the girl on the left to horse near the sisters in the wall of Giovanni Paleologo, and another, presumed, in the Madonna of the Magnificat

Madonna of the Magnificat (Botticelli)

The Madonna of the Magnificat is a painting by the Italian Renaissance master Sandro Botticelli, executed in 1481. It is housed in the Uffizi, Florence.This work portrays the Virgin Mary crowned by two angels...

, where it is represented by the angel on the right-hand side that supports the crown of the Madonna.

On the 8 June 1466, she married Bernardo Rucellai

Bernardo Rucellai

Also known as Bernardus Oricellarius was born in 1448 or 1449 and died on October 7, 1514. An oligarch, banker, ambassador and man-of-letters, his influence was far-reaching...

. Their wedding remained in annals for the magnificent and the profound of festivals and banquets: celebrated in the Loggia Rucellai, constructed from the plans of Leon Alberti Batiste. Together, the couple purchased the Oricellari Gardens. They had four sons, Cosimo, Pietro, Palla and Giovanni.

Nannina de' Medici died in May 1493.