Thomas D. Schiano
Encyclopedia
Thomas D. Schiano, M.D., is an American
specialist in liver transplantation
, intestinal
transplantation and in the diagnosis and treatment of acute and chronic liver disease
. He serves as Associate Editor for the journals Hepatology and Liver Transplantation and has published more than 200 peer-reviewed
articles and abstracts and more than 20 book chapters.
Schiano is currently Professor of Medicine at the Mount Sinai School of Medicine
as well as the Medical Director of Adult Liver Transplantation, Medical Director of Intestinal Transplantation and Director of Clinical Hepatology at the Recanati/Miller Transplantation Institute at the Mount Sinai Medical Center
in New York City
. He is listed among New York Magazine
’s Best Doctors, as well as among the New York Times Magazine
’s list of Super Doctors 2008 -2011.
, New York, on August 12, 1962. He graduated from Fordham University
with a B.S. in biology
and a minor in philosophy
in 1979 and received his M.D. from Universidad Del Noreste Medical School in Tampico, Mexico in 1983. His residency and chief residency in internal medicine were completed at Maimonides Medical Center
and he completed fellowships at Memorial Sloan-Kettering (in clinical nutrition), Temple University
Hospital (in gastroenterology), and Mount Sinai Hospital (in liver disease and liver transplantation).
Schiano is a member of the American Association for the Study of Liver Diseases, the American College of Gastroenterology
, the American Gastroenterological Association
, the American Society for Gastrointestinal Endoscopy
, the New York Organ Donor Network and the American Society of Transplantation
.
Areas of research include liver transplantation, living donor liver transplantation, herbal and drug hepatotoxicity
, nutrition and liver disease, cirrhosis, intestinal transplantation, recurrence of disease post-liver transplantation, treatment of viral hepatitis
post-liver transplantation, herbal and alternative treatments of chronic liver disease, complications of cirrhosis
, portal hypertension
, and cholestasis
associated with TPN.
Schiano is the currently a Principal Investigator on clinical trial A Rollover Protocol to Provide Open-Label Emtricitabine/Tenofovir Disoproxil Fumarate Combination Product to Subjects Completing the GS-US-203-0107 Study, Protocol GS-US-203-0109.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
specialist in liver transplantation
Organ transplant
Organ transplantation is the moving of an organ from one body to another or from a donor site on the patient's own body, for the purpose of replacing the recipient's damaged or absent organ. The emerging field of regenerative medicine is allowing scientists and engineers to create organs to be...
, intestinal
Intestine
In human anatomy, the intestine is the segment of the alimentary canal extending from the pyloric sphincter of the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine...
transplantation and in the diagnosis and treatment of acute and chronic liver disease
Liver disease
Liver disease is a broad term describing any single number of diseases affecting the liver.-Diseases:* Hepatitis, inflammation of the liver, caused mainly by various viruses but also by some poisons , autoimmunity or hereditary conditions...
. He serves as Associate Editor for the journals Hepatology and Liver Transplantation and has published more than 200 peer-reviewed
Peer review
Peer review is a process of self-regulation by a profession or a process of evaluation involving qualified individuals within the relevant field. Peer review methods are employed to maintain standards, improve performance and provide credibility...
articles and abstracts and more than 20 book chapters.
Schiano is currently Professor of Medicine at the Mount Sinai School of Medicine
Mount Sinai School of Medicine
Mount Sinai School of Medicine is an American medical school in the borough of Manhattan in New York City, currently ranked among the top 20 medical schools in the United States. It was chartered by Mount Sinai Hospital in 1963....
as well as the Medical Director of Adult Liver Transplantation, Medical Director of Intestinal Transplantation and Director of Clinical Hepatology at the Recanati/Miller Transplantation Institute at the Mount Sinai Medical Center
Mount Sinai Hospital, New York
Mount Sinai Hospital, founded in 1852, is one of the oldest and largest teaching hospitals in the United States. In 2011-2012, Mount Sinai Hospital was ranked as one of America's best hospitals by U.S...
in New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...
. He is listed among New York Magazine
New York (magazine)
New York is a weekly magazine principally concerned with the life, culture, politics, and style of New York City. Founded by Milton Glaser and Clay Felker in 1968 as a competitor to The New Yorker, it was brasher and less polite than that magazine, and established itself as a cradle of New...
’s Best Doctors, as well as among the New York Times Magazine
The New York Times Magazine
The New York Times Magazine is a Sunday magazine supplement included with the Sunday edition of The New York Times. It is host to feature articles longer than those typically in the newspaper and has attracted many notable contributors...
’s list of Super Doctors 2008 -2011.
Biography
Schiano was born in BrooklynBrooklyn
Brooklyn is the most populous of New York City's five boroughs, with nearly 2.6 million residents, and the second-largest in area. Since 1896, Brooklyn has had the same boundaries as Kings County, which is now the most populous county in New York State and the second-most densely populated...
, New York, on August 12, 1962. He graduated from Fordham University
Fordham University
Fordham University is a private, nonprofit, coeducational research university in the United States, with three campuses in and around New York City. It was founded by the Roman Catholic Diocese of New York in 1841 as St...
with a B.S. in biology
Biology
Biology is a natural science concerned with the study of life and living organisms, including their structure, function, growth, origin, evolution, distribution, and taxonomy. Biology is a vast subject containing many subdivisions, topics, and disciplines...
and a minor in philosophy
Philosophy
Philosophy is the study of general and fundamental problems, such as those connected with existence, knowledge, values, reason, mind, and language. Philosophy is distinguished from other ways of addressing such problems by its critical, generally systematic approach and its reliance on rational...
in 1979 and received his M.D. from Universidad Del Noreste Medical School in Tampico, Mexico in 1983. His residency and chief residency in internal medicine were completed at Maimonides Medical Center
Maimonides Medical Center
Maimonides Medical Center is a non-profit, non-sectarian hospital located in Borough Park, Brooklyn. Maimonides is both a treatment facility and academic medical center with 705 beds, and more than 70 primary care and sub-specialty programs...
and he completed fellowships at Memorial Sloan-Kettering (in clinical nutrition), Temple University
Temple University
Temple University is a comprehensive public research university in Philadelphia, Pennsylvania, United States. Originally founded in 1884 by Dr. Russell Conwell, Temple University is among the nation's largest providers of professional education and prepares the largest body of professional...
Hospital (in gastroenterology), and Mount Sinai Hospital (in liver disease and liver transplantation).
Schiano is a member of the American Association for the Study of Liver Diseases, the American College of Gastroenterology
American College of Gastroenterology
The American College of Gastroenterology is a Bethesda, Maryland-based medical association of gastroenterologists.The association was founded in 1932 and holds annual meetings and regional postgraduate continuing education courses, establishes research grants, and publishes The American Journal of...
, the American Gastroenterological Association
American Gastroenterological Association
The American Gastroenterological Association "AGA" is a medical association of gastroenterologists. About 17,000 scientists and physicians are members of the organization.-Overview:...
, the American Society for Gastrointestinal Endoscopy
American Society for Gastrointestinal Endoscopy
The American Society for Gastrointestinal Endoscopy, or ASGE, is a professional organization of physicians dedicated to improving endoscopy. The ASGE is made up largely of gastroenterologists from the United States. Included in its membership are endoscopists from other medical specialties as well...
, the New York Organ Donor Network and the American Society of Transplantation
American Society of Transplantation
The American Society of Transplantation is an international organization of over 2,700 transplant professionals dedicated to advancing the field of transplantation through the promotion of research, education, advocacy, and organ donation to improve patient care.The AST was founded in 1982 with...
.
Areas of research include liver transplantation, living donor liver transplantation, herbal and drug hepatotoxicity
Hepatotoxicity
Hepatotoxicity implies chemical-driven liver damage.The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses and sometimes even when introduced within therapeutic ranges, may injure...
, nutrition and liver disease, cirrhosis, intestinal transplantation, recurrence of disease post-liver transplantation, treatment of viral hepatitis
Viral hepatitis
Viral hepatitis is liver inflammation due to a viral infection. It may present in acute or chronic forms. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, and Hepatitis E...
post-liver transplantation, herbal and alternative treatments of chronic liver disease, complications of cirrhosis
Cirrhosis
Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules , leading to loss of liver function...
, portal hypertension
Portal hypertension
In medicine, portal hypertension is hypertension in the portal vein and its tributaries.It is often defined as a portal pressure gradient of 10 mmHg or greater.-Causes:Causes can be divided into prehepatic, intrahepatic, and posthepatic...
, and cholestasis
Cholestasis
In medicine, cholestasis is a condition where bile cannot flow from the liver to the duodenum. The two basic distinctions are an obstructive type of cholestasis where there is a mechanical blockage in the duct system such as can occur from a gallstone or malignancy and metabolic types of...
associated with TPN.
Schiano is the currently a Principal Investigator on clinical trial A Rollover Protocol to Provide Open-Label Emtricitabine/Tenofovir Disoproxil Fumarate Combination Product to Subjects Completing the GS-US-203-0107 Study, Protocol GS-US-203-0109.
Honors and awards
Partial list:- 2009, 2011, Best Doctors in America
- 2009, 2010, New York MagazineNew York (magazine)New York is a weekly magazine principally concerned with the life, culture, politics, and style of New York City. Founded by Milton Glaser and Clay Felker in 1968 as a competitor to The New Yorker, it was brasher and less polite than that magazine, and established itself as a cradle of New...
Top Doctors - 2008-2011, New York Super Doctors, the New York Times MagazineThe New York Times MagazineThe New York Times Magazine is a Sunday magazine supplement included with the Sunday edition of The New York Times. It is host to feature articles longer than those typically in the newspaper and has attracted many notable contributors...
- 2008, 2009, 2011, Castle Connolly America’s Top Doctors
- 2006, TRIO (Transplant Recipients International Organization) Manhattan Chapter Triangle Award for Transplant Physicians
- 1995, Sol Sherry Award for Excellence in Basic Research, Temple UniversityTemple UniversityTemple University is a comprehensive public research university in Philadelphia, Pennsylvania, United States. Originally founded in 1884 by Dr. Russell Conwell, Temple University is among the nation's largest providers of professional education and prepares the largest body of professional...
Hospital
Book chapters
Partial list:- Liu J-B, Schiano TD, Miller LS. Upper gastrointestinal tract. In Liu J-B, Goldberg BB (eds): Endoluminal Ultrasound. London, Martin Dunitz Ltd, 1998;147-200.
- Alexander AA, Miller LS, Schiano TD, Liu-J-B. Lower gastrointestinal tract. In Liu J-B, Goldberg BB (eds): Endoluminal Ultrasound. London, Martin Dunitz Ltd, 1998;201-28.
- Miller LS, Schiano TD, Liu J-B. Pancreaticobiliary tract: In Liu J-B, Goldberg BB (eds): Endoluminal Ultrasound. London, Martin Dunitz Ltd, 1998;229-50.
- Schiano TD, Ehrenpreis ED. Gut and hepatobiliary dysfunction: In Hall JB, Schmidt GA, Wood LDH (eds): Principles of Critical Care, 2nd edition, U.S.A., McGraw-Hill, 1998;1221-36.
- Schiano TD, Black M. Drug-induced and toxic liver disease. In Friedman LS, Keeffe EB (eds): Handbook of Liver Disease. London, Churchill Livingstone,1998;103-24. ISBN 0849398967
- Black M, Schiano TD. Management of overlap syndromes. In Krawitt EL (ed): Medical Management of Liver Diseases. New York, Marcel Dekker, Inc. 1999;165-80.
- Schiano TD. Tumors and cysts: In DiBiase JK (ed): Gastroenterology and Hepatology. Pearls of Wisdom. Boston, MA, Boston Medical Publishing Corporation, 2000;255-260.
- Schiano TD, Bodenheimer HC. Complications of chronic liver disease. In Friedman SL, McQuaid KR, Grendell JH (eds): Current Diagnosis and Treatment in Gastroenterology. 2nd edition, USA, McGraw-Hill 2003;639-663.
- Friedman SL, Schiano TD. Cirrhosis and Its Sequelae. In: Goldman L, Ausiello D (eds): Cecil Textbook of Medicine, 22nd edition, Philadelphia, Saunders 2004;936-44.
- Ehrenpreis ED, Schiano TD. Gut and hepatobiliary dysfunction: In Hall JB, Schmidt GA. Wood LDH (eds): Principles of critical care, 3rd edition, USA, McGraw-Hill, 2005;81:1247-1260.
- Schiano TD, Hunt K. Occupational and environmental hepatotoxicity: In Zakim D, Boyer TD: Hepatology. A textbook of liver disease, 5th edition. Saunders/Elsevier, Philadelphia, PA 2006;561-77.
- Liu LU, Schiano TD. Hepatotoxicity of herbal medicines, vitamins, and natural hepatotoxins. Drug-Induced Liver Disease, 2nd ed. Kaplowitz N and DeLeve LD (editors). Informa Healthcare USA, Inc. 2007;733-754.
Publications
Partial list:- Schiano TD, Rhodes R. The dilemma and reality of transplant tourism: an ethical perspective for liver transplant programs. Liver Transpl. 2010 Feb;16(2):113-7. PMID 20104478
- Stanca CM, Montazem AH, Lawal A, Zhang JX, Schiano TD. Intranasal desmopressin versus blood transfusion in cirrhotic patients with coagulopathy undergoing dental extraction: a randomized controlled trial. J Oral Maxillofac Surg. 2010 Jan;68(1):138-43. PMID 20006168
- Ward SC, Schiano TD, Thung SN, Fiel MI. Plasma cell hepatitis in hepatitis C virus patients post-liver transplantation: case-control study showing poor outcome and predictive features in the liver explant. Liver Transpl. 2009 Dec;15(12):1826-33. PMID 19938116
- Massoumi H, Elsiesy H, Khaitova V, Peterson B, Norkus E, Grewal P, Liu L, Chang C, Bach N, Schiano TD. An escalating dose regimen of pegylated interferon and ribavirin in HCV cirrhotic patients referred for liver transplant. Transplantation. 2009 Sep 15;88(5):729-35. PMID 19741473
- Tan HH, Fiel MI, del Rio Martin J, Schiano TD. Graft rejection occurring in post-liver transplant patients receiving cytotoxic chemotherapy: a case series. Liver Transpl. 2009 Jun;15(6):634-9. PMID 19479807
- Fiel MI, Wu HS, Iyer K, Rodriguez-Laiz G, Schiano TD. Rapid reversal of parenteral-nutrition-associated cirrhosis following isolated intestinal transplantation. J Gastrointest Surg. 2009 Sep;13(9):1717-23. Epub 2009 May 6. PMID 19418102
- Hytiroglou P, Gutierrez JA, Freni M, Odin JA, Stanca CM, Merati S, Schiano TD, Branch AD, Thung SN. Recurrence of primary biliary cirrhosis and development of autoimmune hepatitis after liver transplant: A blind histologic study. Hepatol Res. 2009 Jun;39(6):577-84. Epub 2009 Jan 12. PMID 19207586
- Fiel MI, Sauter B, Wu HS, Rodriguez-Laiz G, Gondolesi G, Iyer K, Schiano TD. Regression of hepatic fibrosis after intestinal transplantation in total parenteral nutrition liver disease. Clin Gastroenterol Hepatol. 2008 Aug;6(8):926-33. PMID 18674734
- Wu HS, Fiel MI, Schiano TD, Gil J. Image segmentation of liver fibrosis. J Microsc. 2008 Jul;231(Pt 1):70-80. PMID 18638191
- Killackey MT, Gondolesi GE, Liu LU, Paramesh AS, Thung SN, Suriawinata A, Nguyen E, Roayaie S, Schwartz ME, Emre S, Schiano TD. Effect of ischemia-reperfusion on the incidence of acute cellular rejection and timing of histologic hepatitis C virus recurrence after liver transplantation. Transplant Proc. 2008 Jun;40(5):1504-10. PMID 18589139 Hepatology. 2001 Jan;33(1):3-9.
- Schiano TD, Kim-Schluger L, Gondolesi G, Miller CM. Adult living donor liver transplantation: the hepatologist's perspective. The Mount Sinai Division of Liver Diseases, The Mount Sinai Medical Center, New York, NY 10029, USA. PMID 11124813
- de Boccardo G, Kim JY, Schiano TD, Maurette R, Gagliardi R, Murphy B, Emre S, Akalin E. The burden of chronic kidney disease in long-term liver transplant recipients. Transplant Proc. 2008 Jun;40(5):1498-503. PMID 18589138
- Schiano TD, Rhodes R. Ethics and liver transplantation: a new section in our journal. Liver Transpl. 2008 Jul;14(7):1058-9. PMID 18581483
- Fiel MI, Agarwal K, Stanca C, Elhajj N, Kontorinis N, Thung SN, Schiano TD. Posttransplant plasma cell hepatitis (de novo autoimmune hepatitis) is a variant of rejection and may lead to a negative outcome in patients with hepatitis C virus. Liver Transpl. 2008 Jun;14(6):861-71. PMID 18508382
- Lawal A, Ghobrial R, Te H, Artinian L, Eastwood D, Schiano TD. Comparison of hepatitis C histological recurrence rates and patient survival between split and deceased donor liver transplantation. Transplant Proc. 2007 Dec;39(10):3261-5. PMID 18089367
- Chang CY, Singal AK, Ganeshan SV, Schiano TD, Lookstein R, Emre S. Use of splenic artery embolization to relieve tense ascites following liver transplantation in a patient with paroxysmal nocturnal hemoglobinuria. Liver Transpl. 2007 Nov;13(11):1532-7. PMID 17969202
External links
- The Mount Sinai Medical Center hompage
- The Mount Sinai School of Medicine homepage
- The Recanati/Miller Transplantation Institute at Mount Sinai Medical Center