In the U.S. state

U.S. state

A U.S. state is any one of the 50 federated states of the United States of America that share sovereignty with the federal government. Because of this shared sovereignty, an American is a citizen both of the federal entity and of his or her state of domicile. Four states use the official title of...

 of Indiana

Indiana

Indiana is a US state, admitted to the United States as the 19th on December 11, 1816. It is located in the Midwestern United States and Great Lakes Region. With 6,483,802 residents, the state is ranked 15th in population and 16th in population density. Indiana is ranked 38th in land area and is...

, U.S. Route 50 is a major east–west route. It enters Indiana from Illinois

Illinois

Illinois is the fifth-most populous state of the United States of America, and is often noted for being a microcosm of the entire country. With Chicago in the northeast, small industrial cities and great agricultural productivity in central and northern Illinois, and natural resources like coal,...

 and leaves Indiana into Ohio

Ohio

Ohio is a Midwestern state in the United States. The 34th largest state by area in the U.S.,it is the 7th‑most populous with over 11.5 million residents, containing several major American cities and seven metropolitan areas with populations of 500,000 or more.The state's capital is Columbus...

.

Route description

US 50 enters Indiana over the Wabash River

Wabash River

The Wabash River is a river in the Midwestern United States that flows southwest from northwest Ohio near Fort Recovery across northern Indiana to southern Illinois, where it forms the Illinois-Indiana border before draining into the Ohio River, of which it is the largest northern tributary...

 as a four-lane, limited-access bypass, which was built to interstate

Interstate

An Interstate is a type of high-speed, limited-access highway in the United StatesInterstate may also refer to:-Media:*Interstate 60 , a metaphysical comedy/drama road film...

 standards. US 50 then at a cloverleaf

Cloverleaf

-Places:*Cloverleaf, Louisville, Kentucky, a neighborhood*Cloverleaf, Texas, a suburb of Houston*Cloverleaf Local School District in southern Medina County, Ohio-Science and technology:*A representation of the chemical structure of a transfer RNA molecule...

 interchange

Interchange (road)

In the field of road transport, an interchange is a road junction that typically uses grade separation, and one or more ramps, to permit traffic on at least one highway to pass through the junction without directly crossing any other traffic stream. It differs from a standard intersection, at which...

 with U.S. Route 41

U.S. Route 41 in Indiana

In the U.S. state of Indiana, U.S. Route 41 is a north–south highway that is parallel to the Illinois state line. It enters the state south of Evansville. North of Evansville, it becomes a 4-Lane divided highway passing around Vincennes and traveling North to Terre Haute. In Terre Haute, it...

/U.S. Route 150 has a brief concurrency

Concurrency (road)

A concurrency, overlap, or coincidence in a road network is an instance of one physical road bearing two or more different highway, motorway, or other route numbers...

 with US 50 along the northern outskirts of Vincennes, Indiana. At a trilevel interchange, US 41 heads due south and US 50/US 150, still a four-lane, heads due east toward Washington

Washington, Indiana

Washington is a city in Daviess County, Indiana, United States. The population was 11,509 at the 2010 census. The city is the county seat of Daviess County.-History:...

.

On the way to Washington US 50 passes through intersections with State Road 550

Indiana State Road 550

State Road 550 exists in two portions. The western section is completely within Knox County and has a western terminus east of Emison at U.S. Route 41/U.S. Route 150 and runs southeasterly to the U.S...

 (SR 550) and State Road 241

Indiana State Road 241

State Road 241 in the U.S. state of Indiana is an 18-mile road that runs entirely within Knox County in the southwest corner of the state.-Route description:State Road 244 begins at U.S. Route 41 near Decker...

 (SR 241). US 50 bypasses Washington around the southern edge of town, intersecting State Road 57

Indiana State Road 57

State Road 57 in the U.S. State of Indiana is a north–south, largely two-lane road in the southwestern portion of the state.-Route description:...

 and State Road 257

Indiana State Road 257

State Road 257 is a 31-mile route in Daviess and Pike counties in the U.S. State of Indiana.-Route description:State Road 257 begins in the small town of Stendal. It winds north to pass through Pikeville, Velpen and Otwell. It terminates in Washington....

 (SR 257). Shortly thereafter, theUS 50/US 150 Bypass ends and US 50/US 150 reverts to its original, two-lane route.

In Loogootee

Loogootee, Indiana

-Demographics:As of the census of 2000, there were 2,741 people, 1,226 households, and 712 families residing in the city. The population density was 1,750.5 people per square mile . There were 1,337 housing units at an average density of 853.8 per square mile...

, US 50 has a short concurrency with U.S. Route 231. US 50 heads east from Loogootee towards Shoals

Shoals, Indiana

Shoals is a town in Center and Halbert townships, Martin County, Indiana, United States. The population was 756 at the 2010 census. The city is the county seat of Martin County....

; in Shoals US 150 heads southeast and US 50 heads northeast towards Bedford

Bedford, Indiana

As of the census of 2000, there were 13,768 people, 6,054 households, and 3,644 families residing in the city. The population density was 1,157.1 people per square mile . There were 6,618 housing units at an average density of 556.2 per square mile...

. Southwest of Bedford US 50 begins a concurrency with State Road 37

Indiana State Road 37

State Road 37 in the U.S. State of Indiana is a major route in Indiana, running as a 4-lane divided highway for 110 miles of its course....

 (SR 37). US 50 and SR 37 are concurrent until the intersection with State Road 450

Indiana State Road 450

State Road 450 is a winding route in southern Indiana that terminates at both ends at its parent route, U.S. Route 50. It covers a distance of about .-Route description:...

 (SR 450). SR 37 heads north and US 50 heads east, concurrenct with SR 450, towards downtown Bedford. The concurrency with SR 450 end in downtown Bedford, at the eastern of SR 450.

US 50 heads east from Bedford towards Brownstown

Brownstown, Indiana

Brownstown is a town in Brownstown Township, Jackson County, Indiana, United States. The population was 3,000 at the 2000 census. The city is the county seat of Jackson County. It was named for Jacob Brown, a General of the War of 1812.- History :...

, paasing through an intersection with State Road 446

Indiana State Road 446

State Road 446 is a short highway in the southern portion of the U.S. State of Indiana. Though it is an even-numbered route, it is actually a north–south highway.-Route description:...

, State Road 235

Indiana State Road 235

State Road 235 in the U.S. state of Indiana is a short route in southwest Jackson County.-Route description:State Road 235 begins at State Road 135 east of Medora and southwest of Brownstown. The road travels west to Medora, which it reaches after about . The Medora Covered Bridge parallels the...

, and a concurrency with State Road 135

Indiana State Road 135

State Road 135 in the U.S. State of Indiana is a road that connects Indianapolis with the Ohio River; for the most part it is a two-lane road.-Route description:The southern terminus is the Matthew E. Welsh Bridge on the east side of Mauckport...

. US 50 enters Brownstown and has an intersection with State Road 250

Indiana State Road 250

State Road 250 in the U.S. State of Indiana is a secondary route that runs from U.S. Route 50 in Brownstown eastward toward the Ohio River at State Road 156 in Patriot in southeast Indiana. Towns include Uniontown, Paris Crossing, Canaan, and East Enterprise...

. From Brownstown US 50 heads northeast towards Seymour

Seymour, Indiana

Seymour was the site of the World's First Train Robbery, committed by the local Reno Gang, on October 6, 1866 just east of town. The gang was put into prison for the robbery, and later hanged at Hangman's Crossing outside of town....

. US 50 enters Seymour and becomes a four-lane highway. In Seymour, US 50 has a short concurrency with State Road 11

Indiana State Road 11

State Road 11 in the U.S. State of Indiana is located in south central Indiana and is divided into a northern and southern section. These sections were never connected.- Southern section :...

, an interchange with Interstate 65

Interstate 65 in Indiana

In the U.S. state of Indiana, Interstate 65 traverses the state from south to north. The Indiana portion begins near Louisville, Kentucky and travels north, passing through Columbus, Indianapolis, Lafayette. Interstate 65 terminates near Gary on the Indiana Toll Road. Interstate 65 covers 261.27...

, and an intersection with U.S. Route 31. East of US 50 reverts to a two-lane highway, heading northeast towards North Vernon

North Vernon, Indiana

North Vernon is a city in Jennings County, Indiana, United States. The population was 6,728 at the 2010 census.-Geography:North Vernon is located at ....

.

In North Vernon US 50 has an intersection with State Road 3

Indiana State Road 3

State Road 3 in the U.S. State of Indiana is a discontinuous state road running through east central Indiana from near the Michigan state line to near the Ohio River...

/State Road 7

Indiana State Road 7

State Road 7 in the U.S. State of Indiana is located in southeast Indiana. It runs from northwest-to-southeast connecting the cities of Columbus and Madison.-Route description:...

. US 50 leaves North Vernon heading northeast towards Versailles

Versailles, Indiana

Versailles is a town in Johnson Township, Ripley County, Indiana, United States. The population was 2,113 at the 2010 census. The town is the county seat of Ripley County.-Geography:Versailles is located at...

. Just west of Versailles, US 50 begins a concurrency with U.S. Route 421

U.S. Route 421 in Indiana

U.S. Route 421 enters Indiana from Kentucky, proceeding northwest to Indianapolis, joining Interstate 465, then continuing northwest to Michigan City....

. The concurrency with US 421 ends in Versailles and a concurrency with State Road 129

Indiana State Road 129

State Road 129 is a north–south road in the southeastern part of the U.S. state of Indiana. It traverses Switzerland and Ripley counties connecting Vevay to Batesville.-Route description:...

 begins. The two route head east and then SR 129 heads due north and US 50 heads southeast. US 50 heads toward Dillsboro

Dillsboro, Indiana

Dillsboro is a town in Clay Township, Dearborn County, Indiana, United States. The population was 1,327 at the 2010 census. It was founded in 1830 and named after James Dill, a general in the war of 1812 who beforehand had achieved limited success as a hotel clerk.-Geography:Dillsboro is located at...

, passing through an intersection with State Road 101

Indiana State Road 101

State Road 101 in the U.S. state of Indiana is a north–south state highway in the eastern portion of Indiana that exists in four sections with a combined length of .-First section:...

.

Just east of SR 101, US 50 becomes a four-lane divided highway. In Dillsboro US 50 has an intersection with State Road 62

Indiana State Road 62

State Road 62 in the U.S. State of Indiana is an east–west route that runs from the Illinois state line in the southwest corner of Indiana to the Louisville, Kentucky area, then northeast toward the Cincinnati, Ohio area.-Route description:...

. US 50 heads east towards Aurora

Aurora, Indiana

Aurora is a city in Lawrenceburg and Center townships of Dearborn County, Indiana, United States, along the Ohio River. The population was 3,965 at the 2000 census.-Geography:Aurora is located at ....

, where US 50 has an intersection with State Road 56

Indiana State Road 56

State Road 56 in the U.S. state of Indiana is a route that travels the south central part of the state from west to east.-Route description:...

/State Road 350

Indiana State Road 350

State Road 350 in the U.S. state of Indiana is an east–west state highway in the southeastern corner of Indiana. The road's western terminus is at U.S. Route 421 in Osgood. Its eastern terminus is at U.S. Route 50 in Aurora.-Route description:...

. US 50 heads northeast towards Lawrenceburg

Lawrenceburg, Indiana

Lawrenceburg is a city in Dearborn County, Indiana, United States. The population was 5,042 at the 2010 census. The city is the county seat of Dearborn County...

, passing through intersections with State Road 148

Indiana State Road 148

Indiana State Road 148 in the U.S. state of Indiana is located in Dearborn County in the southeast portion of the state.-Route description:State Road 148 is a short, five-mile route. Though it is an even-numbered route, in practice it runs in a more north–south direction. It begins at...

 (SR 148) and State Road 48

Indiana State Road 48

State Road 48 in the U.S. State of Indiana is an east–west state highway running through southern Indiana. It has three distinct and separate sections. The western terminus of SR 48 is at State Road 63 and the eastern terminus at U.S. Route 50.- Western section :The western section...

 (SR 48).

In Lawrenceburg US 50 has an intersection with State Road 1

Indiana State Road 1

State Road 1 is a north–south state highway in the eastern portion of the U.S. state of Indiana. Its southern terminus is at U.S. Highway 50 in east-central Dearborn County, just east of Lawrenceburg. Its northern terminus is at U.S...

 (SR 1), SR 1 provides access to Interstate 275 (I-275). From Lawrenceburg US 50 heads northeast towards Ohio.

Major intersections