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• I really enjoy forgetting. When I first come to a place, I notice all the little details. I notice the way the sky looks. The color of white paper. The way people walk. Doorknobs. Everything. Then I get used to the place and I don't notice those things anymore. So only by forgetting can I see the place again as it really is.
  • From his film True Stories

• I have something to say about the difference between American and European cities, but I forgot what it was. I have it written down at home somewhere.
  • From his film True Stories

• The better the singer's voice is, the harder it is to believe what they're saying. So I turn my weaknesses into strengths.
  • In the self-interview on Stop Making Sense

• I try to write about small things. Paper, animals, a house…love is kind of big. I have written a love song, though. In this film, I sing it to a lamp.
  • In the self-interview on Stop Making Sense

• Interviewer: If I gave you fifty dollars, right now, what would you do with it?
  David Byrne: I would get something to eat.
  • In the self-interview on Stop Making Sense

• It's like 60 Minutes on acid.
  • In the self-interview on Stop Making Sense

• It's not music you would use to get a girl into bed. If anything, you're going to frighten her off.
  • On the music of Talking Heads, from Channel 4's The 100 Greatest Albums