1913    President Woodrow Wilson addresses American Civil War veterans at the Great Reunion of 1913.

1913    President Woodrow Wilson triggers the explosion of the Gamboa Dike thus ending construction on the Panama Canal.

1913    The Federal Reserve Act is signed into law by President Woodrow Wilson, creating the Federal Reserve.

1915    William Jennings Bryan resigns as Woodrow Wilson's Secretary of State over a disagreement regarding the United States' handling of the sinking of the {{RMS|Lusitania}}.

1915    U.S. President Woodrow Wilson marries Edith Bolling Galt Wilson while president of the United States.

1916    President Woodrow Wilson sends 12,000 United States troops over the U.S.-Mexico border to pursue Pancho Villa.

1916    U.S. President Woodrow Wilson signs a bill incorporating the Boy Scouts of America, making them the only American youth organization with a federal charter.

1917    World War I: President Woodrow Wilson of the still-neutral United States calls for "peace without victory" in Europe.

1917    The Congress of the United States passes the Immigration Act of 1917 over President Woodrow Wilson's veto. Also known as the ''Asiatic Barred Zone Act'', it forbade immigration from nearly all of south and southeast Asia.

1917    World War I: President Woodrow Wilson asks the U.S. Congress for a declaration of war on Germany.

1918    President Woodrow Wilson announces his "Fourteen Points" for the aftermath of World War I.

1918    U.S. President Woodrow Wilson sails for the World War I peace talks in Versailles, becoming the first US president to travel to Europe while in office.

1919    U.S. President Woodrow Wilson suffers a massive stroke, leaving him partially paralyzed.

1919    The U.S. Congress passes the Volstead Act over President Woodrow Wilson's veto, paving the way for Prohibition to begin the following January.