Offseason

• November 6, 1940: Thurman Tucker
  Thurman Tucker
  Thurman Lowell Tucker was an American center fielder in Major League Baseball who played for nine seasons in the American League with the Chicago White Sox and Cleveland Indians. In 701 career games, Tucker recorded a batting average of .255, had 24 triples, 9 home runs, and 179 runs batted in...
  
   was purchased by the White Sox from the Oklahoma City Indians
  Oklahoma City Indians
  The Oklahoma City Indians were an American minor league baseball franchise representing Oklahoma City, Oklahoma, that played in the Texas League in 1909, 1933-42 and from 1946-57, and in the Western League from 1918-32...
  
  .

Regular season

• May 15, 1941: In a game against the Chicago White Sox, Joe DiMaggio
  Joe DiMaggio
  Joseph Paul "Joe" DiMaggio , nicknamed "Joltin' Joe" and "The Yankee Clipper," was an American Major League Baseball center fielder who played his entire 13-year career for the New York Yankees. He is perhaps best known for his 56-game hitting streak , a record that still stands...
  
   of the New York Yankees
  New York Yankees
  The New York Yankees are a professional baseball team based in the The Bronx, New York. They compete in Major League Baseball in the American League's East Division...
  
   began his major league record 56-game hitting streak
  Hitting streak
  In baseball, a hitting streak refers to the number of consecutive official games in which a player gets at least one base hit.According to the Official Baseball Rules, such a streak is ended when a player has at least 1 plate appearance and no hits...
  
   with a hit off Sox pitcher Eddie Smith
  Eddie Smith
  Edgar Smith was a starting pitcher in Major League Baseball who played for the Philadelphia Athletics , Chicago White Sox and Boston Red Sox . Smith was a switch-hitter and threw left-handed...
  
  .

Opening Day lineup

• Bill Knickerbocker
  Bill Knickerbocker
  William Hart Knickerbocker was an American shortstop in Major League Baseball for the Cleveland Indians , St. Louis Browns , New York Yankees , Chicago White Sox and Philadelphia Athletics...
  
  , 2b
• Luke Appling
  Luke Appling
  Lucius Benjamin Appling was an American shortstop in Major League Baseball who played his entire career for the Chicago White Sox . He was elected to the Baseball Hall of Fame in 1964....
  
  , ss
• Joe Kuhel
  Joe Kuhel
  Joseph Anthony Kuhel was a first baseman and manager in Major League Baseball. From 1930 through 1946, Kuhel played for the Washington Senators and Chicago White Sox . He batted and threw left-handed. Following his playing career, Kuhel managed the Washington Senators...
  
  , 1b
• Moose Solters
  Moose Solters
  Julius Joseph "Moose" Solters was a major league outfielder between 1934 and 1943.-Career:...
  
  , lf
• Dario Lodigiani
  Dario Lodigiani
  Dario Antonio Lodigiani [Lodi] was an infielder in Major League Baseball who played for two different teams between 1938 and 1946. Listed at 5'8", 150 lb., he batted and threw right-handed...
  
  , 3b
• Larry Rosenthal
  Larry Rosenthal
  Larry Rosenthal was a professional baseball outfielder in the 1930s and 40's. He first played with the Chicago White Sox in 1936, and hit .281 in 317 at bats. He actually started out spectacularly getting on base three or more times in 19 of his first 50 games, two more than the next four players...
  
  , rf
• Mike Kreevich
  Mike Kreevich
  Michael Andreas "Mike" Kreevich was an American Major League Baseball player who was primarily an outfielder during the 1930s and 1940s. He was born in Mount Olive, Illinois, and batted and threw right-handed.-Career:...
  
  , cf
• Mike Tresh
  Mike Tresh
  Michael "Mike" Tresh was a catcher in Major League Baseball. From 1938 through 1949, he played for the Chicago White Sox and Cleveland Indians . Tresh batted and threw right-handed. He was born in Hazleton, Pennsylvania...
  
  , c
• Bill Dietrich
  Bill Dietrich
  William John "Bullfrog" Dietrich is a former professional baseball player who played pitcher in the Major Leagues from 1933-1948. He would play for the Washington Senators, Chicago White Sox and Philadelphia Athletics.In 16 seasons, Dietrich posted a 108-128 career record...
  
  , p

Notable transactions

• August 1941: Dave Philley
  Dave Philley
  David Earl Philley is a former outfielder who played in Major League Baseball. A switch-hitter who threw right-handed, he debuted on September 6, and played his final game on August 6, . He was born in Paris, Texas....
  
   was purchased by the White Sox from the Monroe White Sox
  Monroe White Sox
  The Monroe White Sox were a Cotton States League baseball team based in Monroe, Louisiana, USA that existed from 1938 to 1941. They were affiliated with the Dallas Steers in 1938 and the Dallas Rebels in 1939. They played their home games at Casino Park....
  
  .

Roster

Starters by position

Other batters

Starting pitchers

Other pitchers

Relief pitchers

Farm system