2C-F
Encyclopedia
2C-F, or 4-fluoro-2,5-dimethoxyphenethylamine
, is a lesser-known psychedelic drug
of the 2C family. It was first synthesized by Alexander Shulgin
. In his book PiHKAL (Phenethylamines i Have Known And Loved)
, the minimum dosage is listed as 250 mg. 2C-F may be found as a brownish freebase oil
, or as a white crystalline hydrochloride salt.
, which would make an active dose of DOF likely to be in the 6-18 milligram range, although it is not known to have been tested in humans.
Phenethylamine
Phenylethylamine or phenethylamine is a natural monoamine alkaloid, trace amine, and also the name of a class of chemicals with many members well known for psychoactive drug and stimulant effects. Studies suggest that phenylethylamine functions as a neuromodulator or neurotransmitter in the...
, is a lesser-known psychedelic drug
Psychedelics, dissociatives and deliriants
This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...
of the 2C family. It was first synthesized by Alexander Shulgin
Alexander Shulgin
Alexander "Sasha" Theodore Shulgin is an American pharmacologist, chemist, artist, and drug developer.Shulgin is credited with the popularization of MDMA, commonly known as ecstasy, in the late 1970s and early 1980s, especially for psychopharmaceutical use and the treatment of depression and...
. In his book PiHKAL (Phenethylamines i Have Known And Loved)
PiHKAL
PiHKAL: A Chemical Love Story is a book by Dr. Alexander Shulgin and Ann Shulgin which was published in 1991. The subject of the work is psychoactive phenethylamine chemical derivatives, notably those that act as psychedelics and/or empathogen-entactogens...
, the minimum dosage is listed as 250 mg. 2C-F may be found as a brownish freebase oil
Oil
An oil is any substance that is liquid at ambient temperatures and does not mix with water but may mix with other oils and organic solvents. This general definition includes vegetable oils, volatile essential oils, petrochemical oils, and synthetic oils....
, or as a white crystalline hydrochloride salt.
Pharmacology
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.Effect
At a dose of 250 milligrams, 2C-F produces modest closed-eye visuals accompanied by lethargy . The amphetamine analogue DOF is likely to be more active than the phenethylamine derivative 2C-F, and in animal trials DOF was found to be 1/6 the dosage of the potent hallucinogen DOI2,5-Dimethoxy-4-iodoamphetamine
2,5-dimethoxy-4-iodoamphetamine is a psychedelic drug and a substituted amphetamine of the phenethylamine family. It is also a powerful anti-inflammatory that is effective at doses on the order of 100 micrograms in humans, far below its effective dose as a psychedelic. Despite being a substituted...
, which would make an active dose of DOF likely to be in the 6-18 milligram range, although it is not known to have been tested in humans.