5,7-Dihydroxytryptamine
Encyclopedia
5,7-Dihydroxytryptamine (5,7-DHT) is a neurotoxin
used to selectively kill serotonergic
neuron
s in scientific research, in the same way that 6-hydroxydopamine (6-OHDA) is used to kill dopaminergic
cell
s.
Neurotoxin
A neurotoxin is a toxin that acts specifically on nerve cells , usually by interacting with membrane proteins such as ion channels. Some sources are more general, and define the effect of neurotoxins as occurring at nerve tissue...
used to selectively kill serotonergic
Serotonergic
Serotonergic or serotoninergic means "related to the neurotransmitter serotonin". A synapse is serotonergic if it uses serotonin as its neurotransmitter...
neuron
Neuron
A neuron is an electrically excitable cell that processes and transmits information by electrical and chemical signaling. Chemical signaling occurs via synapses, specialized connections with other cells. Neurons connect to each other to form networks. Neurons are the core components of the nervous...
s in scientific research, in the same way that 6-hydroxydopamine (6-OHDA) is used to kill dopaminergic
Dopaminergic
Dopaminergic means related to the neurotransmitter dopamine. For example, certain proteins such as the dopamine transporter , vesicular monoamine transporter 2 , and dopamine receptors can be classified as dopaminergic, and neurons which synthesize or contain dopamine and synapses with dopamine...
cell
Cell (biology)
The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....
s.
See also
- 6-Hydroxydopamine (6-OHDA)
- para-Chlorophenylalanine (PCPA)