5-MeO-AMT
Encyclopedia
5-MeO-AMT or 5-methoxy-α-methyltryptamine, α,O-Dimethylserotonin (Alpha-O) is a potent psychedelic
tryptamine. It is soluble in alcohol
.
, the alpha-methylated tryptamine
s can be looked at as the tryptamine homologues of the amphetamines (alpha-methylated phenethylamines).
arrests of the makers
of a huge percentage of the United States' LSD in 2000, 5-MeO-AMT may have occasionally been sold under the guise of LSD in liquid, sugar cube, or blotter
form, though this may be due to DEA reports of finding it on sugar cubes and blotters "LSD Style".
The most common route of administration for 5-MeO-AMT is orally, however anecdotal reports have stated less common methods such as snorting or smoking. Intravenous (IV) and intramuscular (IM) routes are rarely, if ever, used outside research settings due to the high potency, powerful effects and quicker onset.
Erowid lists the following effects:
At higher doses or pending potential allergic/histamine reaction:
High dose side effects:
. It also seems that oral consumption is safer than insufflation
.
Gloria Discerni, 18, died after overdosing on a drug initially believed to be LSD. Authorities learned months later that the drug wasn't LSD but a "designer drug" identified as 5-MeO-AMT.
, 5-MeO-AMT is illegal for human consumption. US DOJ claims it is an analog of 5-MeO-DiPT and alpha-methyltryptamine (AMT), which are Schedule I drugs under the Controlled Substances Act
. According to the Federal Analog Act
(21 U.S.C. § 813), "a controlled substance analog(ue) shall, to the extent intended for human consumption, be treated, for the purposes of any Federal law as a controlled substance in Schedule I." Thus, authorities can prosecute drug offenses involving 5-MeO-AMT in the same manner as offenses involving 5-MeO-DiPT and AMT. (See 21 U.S.C. § 802(32) for the definition of a controlled substance analog(ue).)
Psychedelics, dissociatives and deliriants
This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...
tryptamine. It is soluble in alcohol
Alcohol
In chemistry, an alcohol is an organic compound in which the hydroxy functional group is bound to a carbon atom. In particular, this carbon center should be saturated, having single bonds to three other atoms....
.
Pharmacology
The sympathomimetic effects may in turn be caused by 5-MeO-AMT's structural similarity to the amphetamines. As noted by Alexander ShulginAlexander Shulgin
Alexander "Sasha" Theodore Shulgin is an American pharmacologist, chemist, artist, and drug developer.Shulgin is credited with the popularization of MDMA, commonly known as ecstasy, in the late 1970s and early 1980s, especially for psychopharmaceutical use and the treatment of depression and...
, the alpha-methylated tryptamine
Tryptamine
Tryptamine is a monoamine alkaloid found in plants, fungi, and animals. It is based around the indole ring structure, and is chemically related to the amino acid tryptophan, from which its name is derived...
s can be looked at as the tryptamine homologues of the amphetamines (alpha-methylated phenethylamines).
Recreational usage
5-MeO-AMT is supposedly sold in 4 mg tablets by the street name Alpha-O and taken as a recreational drug. Since the DEADrug Enforcement Administration
The Drug Enforcement Administration is a federal law enforcement agency under the United States Department of Justice, tasked with combating drug smuggling and use within the United States...
arrests of the makers
William Leonard Pickard
William Leonard Pickard is one of two people convicted in the largest lysergic acid diethylamide manufacturing case in history. In 2000, while moving the LSD laboratory, Pickard and Clyde Apperson were pulled over while driving a Ryder rental truck and a follow car...
of a huge percentage of the United States' LSD in 2000, 5-MeO-AMT may have occasionally been sold under the guise of LSD in liquid, sugar cube, or blotter
Blotter
Blotter can mean several things:-*For a desk blotter, see desk pad*For blotter acid, see LSD*For an antique blotter associated with a quill pen, see fountain pen and blotting paper....
form, though this may be due to DEA reports of finding it on sugar cubes and blotters "LSD Style".
The most common route of administration for 5-MeO-AMT is orally, however anecdotal reports have stated less common methods such as snorting or smoking. Intravenous (IV) and intramuscular (IM) routes are rarely, if ever, used outside research settings due to the high potency, powerful effects and quicker onset.
Effects
The effects of 5-MeO-AMT occur at 4–7 mg orally for most users.Erowid lists the following effects:
Positive
- Increased energy
- Improved mood heading into euphoria at higher doses
- Increased sociability, gregariousness
- Increased giggling and laughing
- Increased sense of creative thinking
- Increased pleasure from sense of touch
- Intensification in sexSexIn biology, sex is a process of combining and mixing genetic traits, often resulting in the specialization of organisms into a male or female variety . Sexual reproduction involves combining specialized cells to form offspring that inherit traits from both parents...
ual / erotic experiences for some users
Neutral
- Light headedness
- Brightening of colorColorColor or colour is the visual perceptual property corresponding in humans to the categories called red, green, blue and others. Color derives from the spectrum of light interacting in the eye with the spectral sensitivities of the light receptors...
s - Visuals including motionMotion (physics)In physics, motion is a change in position of an object with respect to time. Change in action is the result of an unbalanced force. Motion is typically described in terms of velocity, acceleration, displacement and time . An object's velocity cannot change unless it is acted upon by a force, as...
, wavesWAVESThe WAVES were a World War II-era division of the U.S. Navy that consisted entirely of women. The name of this group is an acronym for "Women Accepted for Volunteer Emergency Service" ; the word "emergency" implied that the acceptance of women was due to the unusual circumstances of the war and...
, breathing walls, etc (usually at doses over 4–5 mg) - Increased attention on details
- Auditory distortions or hallucinations (usually at higher doses)
Negative
Expected at any dose:- HeadacheHeadacheA headache or cephalalgia is pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions of the head and neck. The brain tissue itself is not sensitive to pain because it lacks pain receptors. Rather, the pain is caused by disturbance of the...
- Body fatigue
- Chills from slightly elevated body temperature (potential dehydration)
- Stress and extreme fatigue from long duration of effects.
At higher doses or pending potential allergic/histamine reaction:
- NauseaNauseaNausea , is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It often, but not always, precedes vomiting...
, diarrheaDiarrheaDiarrhea , also spelled diarrhoea, is the condition of having three or more loose or liquid bowel movements per day. It is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause dehydration and... - Vomiting at high doses
High dose side effects:
- Difficulty sleepSleepSleep is a naturally recurring state characterized by reduced or absent consciousness, relatively suspended sensory activity, and inactivity of nearly all voluntary muscles. It is distinguished from quiet wakefulness by a decreased ability to react to stimuli, and is more easily reversible than...
ing or resting for 12–24 hours after ingestion. - ParanoiaParanoiaParanoia [] is a thought process believed to be heavily influenced by anxiety or fear, often to the point of irrationality and delusion. Paranoid thinking typically includes persecutory beliefs, or beliefs of conspiracy concerning a perceived threat towards oneself...
, irritability, anxietyAnxietyAnxiety is a psychological and physiological state characterized by somatic, emotional, cognitive, and behavioral components. The root meaning of the word anxiety is 'to vex or trouble'; in either presence or absence of psychological stress, anxiety can create feelings of fear, worry, uneasiness,...
(increasing with dose). - Delusional, aggressive, or dissociated behaviour at very high doses (20+ mg)
Dangers
If misrepresented as LSD, 5-MeO-AMT can be extremely dangerous; users may take a number of "hits" of 5-MeO-AMT, assuming that it is LSD. Unlike LSD, which is considerably safer in overdose, 5-MeO-AMT can be very harmful or fatal. Particularly sensitive individuals can experience symptoms of overdose at dosages in the normal (for most users) range — as low as 20 mg. This has led to at least a few hospitalizations and possibly more than one death. It is likely that the overdose potential of the compound is due to its sympathomimetic effects, as the side effects noted in overdose cases include cardiac arrhythmia and seizureSeizure
An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain". The outward effect can be as dramatic as a wild thrashing movement or as mild as a brief loss of awareness...
. It also seems that oral consumption is safer than insufflation
Insufflation (medicine)
Insufflation is the practice of inhaling a substance. Insufflation has limited medical use, but is a common route of administration with many respiratory drugs used to treat conditions in the lungs and paranasal sinus .The technique is common for many recreational drugs and is also used for some...
.
Gloria Discerni, 18, died after overdosing on a drug initially believed to be LSD. Authorities learned months later that the drug wasn't LSD but a "designer drug" identified as 5-MeO-AMT.
Legality
According to the US Department of JusticeUnited States Department of Justice
The United States Department of Justice , is the United States federal executive department responsible for the enforcement of the law and administration of justice, equivalent to the justice or interior ministries of other countries.The Department is led by the Attorney General, who is nominated...
, 5-MeO-AMT is illegal for human consumption. US DOJ claims it is an analog of 5-MeO-DiPT and alpha-methyltryptamine (AMT), which are Schedule I drugs under the Controlled Substances Act
Controlled Substances Act
The Controlled Substances Act was enacted into law by the Congress of the United States as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970. The CSA is the federal U.S. drug policy under which the manufacture, importation, possession, use and distribution of certain...
. According to the Federal Analog Act
Federal Analog Act
The Federal Analog Act, , is a controversial section of the United States Controlled Substances Act which allowed any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were also listed in those schedules, but only if intended for human...
(21 U.S.C. § 813), "a controlled substance analog(ue) shall, to the extent intended for human consumption, be treated, for the purposes of any Federal law as a controlled substance in Schedule I." Thus, authorities can prosecute drug offenses involving 5-MeO-AMT in the same manner as offenses involving 5-MeO-DiPT and AMT. (See 21 U.S.C. § 802(32) for the definition of a controlled substance analog(ue).)
See also
- 5-MeO-DMT5-MeO-DMT5-MeO-DMT is a powerful psychedelic tryptamine. It is found in a wide variety of plant and psychoactive toad species and, like its close relatives DMT and bufotenin , it has been used as an entheogen by South American shamans for thousands of years.-Chemistry:5-MeO-DMT was first synthesized in...
- 5-MeO-DPT5-MeO-DPT5-MeO-DPT , is a hallucinogenic and entheogenic drug.-Chemistry:The full chemical name is N-[2-ethyl]-N-propylpropan-1-amine...
- 5-MeO-DiPT
- AMT