ACER2
Encyclopedia
Alkaline ceramidase 2 also known as ACER2 is a ceramidase
enzyme which in humans is encoded by the ACER2 gene
.
pathway plays an important role in regulating integrin β1 subunit (ITGB1) maturation and cell adhesion
mediated by β1 integrins.
Ceramidase
Ceramidase is an enzyme which cleaves fatty acids from ceramide, producing sphingosine which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate .- Function :...
enzyme which in humans is encoded by the ACER2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
The ACER2/sphingosineSphingosine
Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.-Functions:...
pathway plays an important role in regulating integrin β1 subunit (ITGB1) maturation and cell adhesion
Cell adhesion
Cellular adhesion is the binding of a cell to a surface, extracellular matrix or another cell using cell adhesion molecules such as selectins, integrins, and cadherins. Correct cellular adhesion is essential in maintaining multicellular structure...
mediated by β1 integrins.