AG 489
Encyclopedia
AG 489 is a component of the venom
Venom
Venom is the general term referring to any variety of toxins used by certain types of animals that inject it into their victims by the means of a bite or a sting...

 produced by Agelenopsis aperta. It inhibits the ligand gated ion channel TRPV1
TRPV1
The transient receptor potential cation channel subfamily V member 1 ', also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene...

through a pore blocking mechanism.
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