AR-R17779
Encyclopedia
AR-R17779 is a drug that acts as a potent and selective full agonist for the α7
subtype of neural nicotinic acetylcholine receptor
s. It has nootropic
effects in animal studies, but its effects do not substitute for those of nicotine
. It has also recently been studied as a potential novel treatment for arthritis
.
Alpha-7 nicotinic receptor
The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor, consisting entirely of α7 subunits....
subtype of neural nicotinic acetylcholine receptor
Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction...
s. It has nootropic
Nootropic
Nootropics , also referred to as smart drugs, brain steroids, memory enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration...
effects in animal studies, but its effects do not substitute for those of nicotine
Nicotine
Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...
. It has also recently been studied as a potential novel treatment for arthritis
Arthritis
Arthritis is a form of joint disorder that involves inflammation of one or more joints....
.