ATC code N04
Encyclopedia
N04AA Tertiary amines
- N04AA01 TrihexyphenidylTrihexyphenidylTrihexyphenidyl , also known as benzhexol, is an antiparkinsonian agent of the antimuscarinic class. It has been in clinical usage for decades...
- N04AA02 BiperidenBiperidenBiperiden is an antiparkinsonian agent of the anticholinergic type. The original brand name, which still exists and is manufactured by BASF/Knoll Pharma, is Akineton. Generics are available worldwide.- Pharmacokinetics :...
- N04AA03 MetixeneMetixeneMetixene, also known as methixene, is an anticholinergic used as an antiparkinsonian agent.Schmutz, J.; 1959, ....
- N04AA04 Procyclidine
- N04AA05 Profenamine
- N04AA08 DexetimideDexetimideDexetimide is a piperidine anticholinergic. It is a muscarinic antagonist that has been used to treat neuroleptic-induced Parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968....
- N04AA09 PhenglutarimidePhenglutarimidePhenglutarimide is a anticholinergic used as an antiparkinsonian agent....
- N04AA10 MazaticolMazaticolMazaticol is a anticholinergic used as an antiparkinsonian agent in Japan.- External links :*...
- N04AA11 BornaprineBornaprineBornaprine is an anticholinergic used as an antiparkinsonian agent....
- N04AA12 TropatepineTropatepineTropatepine is a anticholinergic used as an antiparkinsonian agent....
N04AB EtherEtherEthers are a class of organic compounds that contain an ether group — an oxygen atom connected to two alkyl or aryl groups — of general formula R–O–R'. A typical example is the solvent and anesthetic diethyl ether, commonly referred to simply as "ether"...
s chemically close to antihistamineAntihistamineAn H1 antagonist is a histamine antagonist of the H1 receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions...
s
- N04AB01 EtanautineEtanautineEtanautine, also known as diphenhydramine monoacefyllinate, is an anticholinergic used as an antiparkinsonian agent. It is a 1:1 salt of diphenhydramine with acefylline, similar to the diphenhydramine/8-chlorotheophylline combination product dimenhydrinate.As with dimenhydrinate, the stimulant...
- N04AB02 OrphenadrineOrphenadrineOrphenadrine is an anticholinergic drug of the ethanolamine antihistamine class with prominent CNS and peripheral actions used to treat painful muscle spasms, other similar conditions, as well as the treatment...
(chloride)
N04AC Ethers of tropineTropineTropine is a derivative of tropane containing a hydroxyl group at third carbon. It is also called 3-tropanol.Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, a cholinergic drug prototypical of the muscarinic antagonist class.-External Links:*...
or tropine derivatives
- N04AC01 Benzatropine
- N04AC30 EtybenzatropineEtybenzatropineEtybenzatropine , also known as ethybenztropine and tropethydrylin, is an anticholinergic/antihistamine marketed under the trade names Panolid, Ponalid, and Ponalide, which is used as an antiparkinsonian agent. Like its analogue benzatropine, it may act as a dopamine reuptake inhibitor.-...
N04BA Dopa and dopa derivatives
- N04BA01 LevodopaLevodopaL-DOPA is a chemical that is made and used as part of the normal biology of some animals and plants. Some animals including humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine , and epinephrine collectively...
- N04BA02 Levodopa and decarboxylase inhibitor
- N04BA03 Levodopa, decarboxylase inhibitor and COMT inhibitorCOMT inhibitorA COMT inhibitor is a drug that inhibits the action of catechol-O-methyl transferase. This enzyme is involved in degrading neurotransmitters. COMT inhibitors are used in the treatment of Parkinson's disease....
- N04BA04 MelevodopaMelevodopaMelevodopa is a dopaminergic agent. It is the methyl ester of levodopa....
- N04BA05 Melevodopa and decarboxylase inhibitor
- N04BA06 EtilevodopaEtilevodopaEtilevodopa is a dopaminergic agent. It is the ethyl ester of levodopa....
and decarboxylase inhibitor
N04BC Dopamine agonists
- N04BC01 BromocriptineBromocriptineBromocriptine , an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease , hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.- Indications :Amenorrhea, female infertility, galactorrhea, hypogonadism, and acromegaly...
- N04BC02 PergolidePergolidePergolide is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease....
- N04BC03 Dihydroergocryptine mesylate
- N04BC04 RopiniroleRopiniroleRopinirole is a non-ergoline dopamine agonist. It is manufactured by GlaxoSmithKline , Cipla and Sun Pharmaceutical. It is used in the treatment of Parkinson's disease...
- N04BC05 PramipexolePramipexolePramipexole is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease and restless legs syndrome...
- N04BC06 CabergolineCabergolineCabergoline , an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. In vitro, rat studies show cabergoline has a direct inhibitory effect on pituitary lactotroph cells...
- N04BC07 ApomorphineApomorphineApomorphine is a non-selective dopamine agonist which activates both D1-like and D2-like receptors, with some preference for the latter subtypes. It is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix...
- N04BC08 PiribedilPiribedilPiribedil is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist...
- N04BC09 RotigotineRotigotineRotigotine is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease and restless legs syndrome in Europe and the United States...
N04BD Monoamine oxidase B inhibitorsMonoamine oxidase inhibitorMonoamine oxidase inhibitors are a class of antidepressant drugs prescribed for the treatment of depression. They are particularly effective in treating atypical depression....
- N04BD01 SelegilineSelegilineSelegiline is a drug used for the treatment of early-stage Parkinson's disease, depression and senile dementia. In normal clinical doses it is a selective irreversible MAO-B inhibitor, however in larger doses it loses its specificity and also inhibits MAO-A...
- N04BD02 RasagilineRasagilineRasagiline is an irreversible inhibitor of monoamine oxidase used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. It is selective for MAO type B over type A by a factor of fourteen....
N04BX Other dopaminergic agents
- N04BX01 TolcaponeTolcaponeTolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase . - Uses :Tolcapone is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.- Chemistry :...
- N04BX02 EntacaponeEntacaponeEntacapone is a drug that functions as a catechol-O-methyl transferase inhibitor. It is used in the treatment of Parkinson's disease....
- N04BX03 BudipineBudipineBudipine is an antiparkinson agent.Its mechanism of action is not well characterized. It is believed to be an NMDA receptor antagonist, however, promoting the synthesis of dopamine....