Adolor Corporation
Encyclopedia
Adolor Corporation is a biopharmaceutical
company specializing in the discovery, development and commercialization of prescription
pain management
products.
Adolor Corporation is a biopharmaceutical company specializing in the discovery, development and commercialization of novel prescription pain management products.
Adolor’s first approved product in the United States is Entereg, which is indicated to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. Entereg is available for short-term use in hospitals registered under the Entereg Access Support and Education (E.A.S.E.TM) Program. In collaboration with GlaxoSmithKline, the Company launched Entereg in mid-2008.
The Company’s research and development pipeline includes: two novel delta opioid receptor agonists, currently in mid-stage clinical development in collaboration with Pfizer Inc. for chronic pain; a mu opioid receptor antagonist entering development for chronic opioid bowel dysfunction (OBD); and several opioid and non-opioid discovery programs. Adolor has two lead product candidates in development: Entereg (alvimopan) for the
management of the gastrointestinal side effects associated with opioid
use; and, Delta opioid receptor agonists for a variety of pain indications. Adolor and GlaxoSmithKline
are collaborating in the worldwide development and commercialization of Entereg in multiple indications. The drug is being reviewed by the Food and Drug Administration
, and the process is expected to be completed in May 2008. Adolor and Pfizer
are collaborating in the worldwide development and commercialization of two Delta agonists for pain. Adolor also has a number of discovery research programs focused on the identification of novel compounds for the treatment of pain.
Adolor has its headquarters in in Exton, PA.
Biopharmaceutical
Biopharmaceuticals are medical drugs produced using biotechnology. They include proteins , nucleic acids and living microorganisms like virus and bacteria where the virulence of viruses and bacteria is reduced by the process of attenuation, they can be used for therapeutic or in vivo diagnostic...
company specializing in the discovery, development and commercialization of prescription
Prescription drug
A prescription medication is a licensed medicine that is regulated by legislation to require a medical prescription before it can be obtained. The term is used to distinguish it from over-the-counter drugs which can be obtained without a prescription...
pain management
Pain management
Pain management is a branch of medicine employing an interdisciplinary approach for easing the suffering and improving the quality of life of those living with pain. The typical pain management team includes medical practitioners, clinical psychologists, physiotherapists, occupational therapists,...
products.
Adolor Corporation is a biopharmaceutical company specializing in the discovery, development and commercialization of novel prescription pain management products.
Adolor’s first approved product in the United States is Entereg, which is indicated to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis. Entereg is available for short-term use in hospitals registered under the Entereg Access Support and Education (E.A.S.E.TM) Program. In collaboration with GlaxoSmithKline, the Company launched Entereg in mid-2008.
The Company’s research and development pipeline includes: two novel delta opioid receptor agonists, currently in mid-stage clinical development in collaboration with Pfizer Inc. for chronic pain; a mu opioid receptor antagonist entering development for chronic opioid bowel dysfunction (OBD); and several opioid and non-opioid discovery programs. Adolor has two lead product candidates in development: Entereg (alvimopan) for the
management of the gastrointestinal side effects associated with opioid
Opioid
An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract...
use; and, Delta opioid receptor agonists for a variety of pain indications. Adolor and GlaxoSmithKline
GlaxoSmithKline
GlaxoSmithKline plc is a global pharmaceutical, biologics, vaccines and consumer healthcare company headquartered in London, United Kingdom...
are collaborating in the worldwide development and commercialization of Entereg in multiple indications. The drug is being reviewed by the Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
, and the process is expected to be completed in May 2008. Adolor and Pfizer
Pfizer
Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...
are collaborating in the worldwide development and commercialization of two Delta agonists for pain. Adolor also has a number of discovery research programs focused on the identification of novel compounds for the treatment of pain.
Adolor has its headquarters in in Exton, PA.