An Adrenergic antagonist is a pharmaceutical substance that acts to inhibit the action of the adrenergic receptor

Adrenergic receptor

The adrenergic receptors are a class of metabotropic G protein-coupled receptors that are targets of the catecholamines, especially noradrenaline and adrenaline ....

s. It is thus a type of sympatholytic

Sympatholytic

A sympatholytic drug is a medication which inhibits the postganglionic functioning of the sympathetic nervous system . They are indicated for various functions, for example they may be used as antihypertensives...

.

It has the opposite effect as adrenergic agonists.

More specifically, they can be divided into:

• Alpha blocker
  Alpha blocker
  Alpha-1 blockers constitute a variety of drugs which block α1-adrenergic receptors in arteries and smooth muscles.-Pharmacology:...
  
  s
• Beta blocker
  Beta blocker
  Beta blockers or beta-adrenergic blocking agents, beta-adrenergic antagonists, beta-adrenoreceptor antagonists or beta antagonists, are a class of drugs used for various indications. They are particularly for the management of cardiac arrhythmias, cardioprotection after myocardial infarction ,...
  
  s

Structure Activity Relationship

If the amine on the Adrenergic agent has a substituent bigger than a tertiary butyl, then the compound becomes an adrenergic antagonist.

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