Anita Harding
Overview
 
Anita Harding was a British
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...

 neurologist
Neurologist
A neurologist is a physician who specializes in neurology, and is trained to investigate, or diagnose and treat neurological disorders.Neurology is the medical specialty related to the human nervous system. The nervous system encompasses the brain, spinal cord, and peripheral nerves. A specialist...

. She was born in Birmingham and educated at the King Edward VI High School for Girls
King Edward VI High School for Girls
King Edward VI High School for Girls is an independent secondary school in Edgbaston, Birmingham, England. It is part of the Foundation of the Schools of King Edward VI in Birmingham and occupies the same site as, and is twinned with, King Edward's School...

 and the Royal Free Hospital Medical School, where she qualified in 1975. She married neurology professor P.K. Thomas two years later, and trained as a neurologist.

Harding made several significant contributions in the field of inherited neurologic disorders. Her major achievements were the classification of the peripheral neuropathies
Peripheral neuropathy
Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of or trauma to the nerve or the side-effects of systemic illness....

 and hereditary ataxias, the first identification of a mitochondrial DNA
Mitochondrial DNA
Mitochondrial DNA is the DNA located in organelles called mitochondria, structures within eukaryotic cells that convert the chemical energy from food into a form that cells can use, adenosine triphosphate...

 mutation
Mutation
In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic...

 in human disease (in Kearns-Sayre syndrome
Kearns-Sayre syndrome
Kearns–Sayre syndrome also known as oculocraniosomatic disease or Oculocraniosomatic neuromuscular disease with ragged red fibers is a mitochondrial myopathy with a typical onset before 20 years of age...

) and the identification of trinucleotide repeats in degenerative neurologic diseases (e.g.
 
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