Anthony Nolan
Encyclopedia
Anthony Nolan is a UK
charity
that focuses on leukaemia and Hematopoietic stem cell transplantation. It manages and recruits donors to one of the two bone marrow
registers in the United Kingdom; the other register is the British Bone Marrow Registry run by the National Blood Service
. It also carries out pioneering research to help make bone marrow transplants more effective.
The charity is named after Anthony Nolan (born 1971, died 1979), who did not suffer from leukaemia but from Wiskott-Aldrich syndrome
, a rare inherited blood disorder. It was founded by Anthony's mother Shirley (1942–2002) in 1974 as the "Anthony Nolan Register". Initially based at the Westminster Children's Hospital
, it moved to St Mary Abbot's Hospital
in 1978 and to its present offices, laboratory and research institute in north London, in the grounds of the Royal Free Hospital. The charity was renamed in 2001 to the "Anthony Nolan Trust". and again in 2010 to "Anthony Nolan".
It is a priority for Anthony Nolan to recruit more male donors because men can generally provide greater volumes of blood stem cells than female donors. This helps faster engraftment and the reconstitution of the immune system post-transplant. If there is a choice of donor for a patient in most cases a male donor will be preferred. It is also the only register in the UK to allow gay men to join, subject to their normal criteria for inclusion.
The Midland Metro
has a tram
named after Anthony Nolan.
Daniel De Gale
(1987–2008), a leukaemia patient, inspired his mother Beverley and her partner, Orin Lewis, to set up the African-Caribbean Leukaemia Trust
in June 1996. ACLT worked "in partnership with the ... Nolan Trust" to build the number of bone marrow donors, specifically of African, African Caribbean, and mixed parentage on the UK register.
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...
charity
Charitable organization
A charitable organization is a type of non-profit organization . It differs from other types of NPOs in that it centers on philanthropic goals A charitable organization is a type of non-profit organization (NPO). It differs from other types of NPOs in that it centers on philanthropic goals A...
that focuses on leukaemia and Hematopoietic stem cell transplantation. It manages and recruits donors to one of the two bone marrow
Bone marrow
Bone marrow is the flexible tissue found in the interior of bones. In humans, bone marrow in large bones produces new blood cells. On average, bone marrow constitutes 4% of the total body mass of humans; in adults weighing 65 kg , bone marrow accounts for approximately 2.6 kg...
registers in the United Kingdom; the other register is the British Bone Marrow Registry run by the National Blood Service
National Blood Service
The National Blood Service is the organisation for England and North Wales which collects blood and other tissues, tests, processes, and supplies all the hospitals in England and North Wales...
. It also carries out pioneering research to help make bone marrow transplants more effective.
The charity is named after Anthony Nolan (born 1971, died 1979), who did not suffer from leukaemia but from Wiskott-Aldrich syndrome
Wiskott-Aldrich syndrome
Wiskott–Aldrich syndrome is a rare X-linked recessive disease characterized by eczema, thrombocytopenia , immune deficiency, and bloody diarrhea . It is also sometimes called the eczema-thrombocytopenia-immunodeficiency syndrome in keeping with Aldrich's original description in 1954...
, a rare inherited blood disorder. It was founded by Anthony's mother Shirley (1942–2002) in 1974 as the "Anthony Nolan Register". Initially based at the Westminster Children's Hospital
Chelsea and Westminster Hospital
Chelsea and Westminster Hospital is a public hospital located on Fulham Road, in the Chelsea area of London, England. It is managed by the Chelsea and Westminster Hospital NHS Foundation Trust, and opened in May 1993.-History:...
, it moved to St Mary Abbot's Hospital
St Mary Abbot's Hospital
St Mary Abbot's Hospital, Marloes Road, Kensington, London, functioned from 1871 to 1992. Although closed as a hospital, it still has an Ear Nose and Throat department specifically dealing with hearing aids....
in 1978 and to its present offices, laboratory and research institute in north London, in the grounds of the Royal Free Hospital. The charity was renamed in 2001 to the "Anthony Nolan Trust". and again in 2010 to "Anthony Nolan".
It is a priority for Anthony Nolan to recruit more male donors because men can generally provide greater volumes of blood stem cells than female donors. This helps faster engraftment and the reconstitution of the immune system post-transplant. If there is a choice of donor for a patient in most cases a male donor will be preferred. It is also the only register in the UK to allow gay men to join, subject to their normal criteria for inclusion.
The Midland Metro
Midland Metro
The Midland Metro is a light-rail or tram line in the West Midlands of England between the cities of Birmingham and Wolverhampton via West Bromwich and Wednesbury. It is owned and promoted by Centro, and operated by West Midlands Travel Limited, a subsidiary of the National Express Group , under...
has a tram
Tram
A tram is a passenger rail vehicle which runs on tracks along public urban streets and also sometimes on separate rights of way. It may also run between cities and/or towns , and/or partially grade separated even in the cities...
named after Anthony Nolan.
Daniel De Gale
Daniel De Gale
Daniel David De Gale inspired a major push to promote awareness of Leukaemia in the United Kingdom's black community when, as a child, his mother and stepfather launched a search for suitable bone marrow donors and a charity....
(1987–2008), a leukaemia patient, inspired his mother Beverley and her partner, Orin Lewis, to set up the African-Caribbean Leukaemia Trust
African-Caribbean Leukaemia Trust
The African-Caribbean Leukaemia Trust is a United Kingdom based charity established in June 1996 by Beverly De-Gale and Orin Lewis, the parents of Daniel De Gale....
in June 1996. ACLT worked "in partnership with the ... Nolan Trust" to build the number of bone marrow donors, specifically of African, African Caribbean, and mixed parentage on the UK register.
See also
- Professor John Raymond HobbsJohn Raymond HobbsJohn Raymond Hobbs MRCS, FRCP, FRCPath, FRCPaed was a professor who was at the forefront of the techniques of Clinical Immunology, Protein Biochemistry and Bone Marrow Transplantation, specifically in Child Health.-Early life:...
, whose team set up the world's first bone marrow donor register. - Professor Sydney Selwyn, who was closely involved with the treatment of Anthony Nolan.