Arenobufagin
Encyclopedia
Arenobufagin is a cardiotoxic bufanolide
steroid
secreted by the Argentine toad
Bufo arenarum. It has effects similar to digitalis
, blocking the Na+/K+ pump in heart tissue.
Bufanolide
Bufadienolide is a type of steroid. Its derivatives are collectively known as bufadienolides, including many in the form of bufadienolide glycosides . These are a type of cardiac glycoside, the other being the cardenolide gylcosides...
steroid
Steroid
A steroid is a type of organic compound that contains a characteristic arrangement of four cycloalkane rings that are joined to each other. Examples of steroids include the dietary fat cholesterol, the sex hormones estradiol and testosterone, and the anti-inflammatory drug dexamethasone.The core...
secreted by the Argentine toad
Toad
A toad is any of a number of species of amphibians in the order Anura characterized by dry, leathery skin , short legs, and snoat-like parotoid glands...
Bufo arenarum. It has effects similar to digitalis
Digitalis
Digitalis is a genus of about 20 species of herbaceous perennials, shrubs, and biennials that are commonly called foxgloves. This genus was traditionally placed in the figwort family Scrophulariaceae, but recent reviews of phylogenetic research have placed it in the much enlarged family...
, blocking the Na+/K+ pump in heart tissue.