First generation

• Cliff Arquette
  Cliff Arquette
  Clifford Charles Arquette was an actor and comedian, famous for his role as Charley Weaver.-Early life and career:...
  
   (December 26, 1904 – September 23, 1974) – TV actor, father of Lewis Arquette and grandfather of David, Richmond, Rosanna, Alexis and Patricia

Second generation

• Lewis Arquette
  Lewis Arquette
  Lewis Michael Arquette was an American film actor, writer and producer. Arquette was known for playing "J.D. Pickett" on the TV series, The Waltons, where he worked from 1978–1981.-Life and career:...
  
   (December 14, 1935 – February 10, 2001) – movie actor, son of Cliff Arquette and father of the Arquette children

Third generation

• Rosanna Arquette
  Rosanna Arquette
  Rosanna Lauren Arquette is an American actress, film director, and producer.-Early life:Arquette was born in New York City, the daughter of Brenda Olivia "Mardi" , an actress, poet, theater operator, activist, acting teacher, and therapist, and Lewis Arquette, an actor and director. Her paternal...
  
   (August 10, 1959) – movie actress
• Richmond Arquette
  Richmond Arquette
  - Background :Arquette was born in New York City, the son of Brenda "Mardi" Olivia , an actress, poet, theater operator, activist, acting teacher and therapist, and Lewis Arquette, an actor. Arquette's paternal grandfather was comedian Cliff Arquette...
  
   (August 21, 1963) – movie actor
• Patricia Arquette
  Patricia Arquette
  Patricia T. Arquette is an American actress and director. She played the lead character in the supernatural drama series Medium for which she won the Primetime Emmy Award for Outstanding Lead Actress in a Drama Series....
  
   (April 8, 1968) – movie and TV actress
• Alexis Arquette
  Alexis Arquette
  Alexis Arquette is an American trans woman, actress, musician, and cabaret performer.-Early life:...
  
   (July 28, 1969) – movie actress
• David Arquette
  David Arquette
  David Arquette is an American actor, film director, producer, screenwriter, fashion designer, and occasional professional wrestler. A member of the Arquette acting family, he first became known during the mid 1990s after starring in several Hollywood films, such as the Scream series, Wild Bill and...
  
   (September 8, 1971) – movie actor and TV director

Others

• James Newton Howard
  James Newton Howard
  James Newton Howard is an American composer best known for his scores to motion pictures. He is one of the most popular and respected composers for cinema, and has scored over 100 films...
  
   (June 9, 1951) – composer and orchestrator, ex-husband to Rosanna (1986–87)
• Nicolas Cage
  Nicolas Cage
  Nicolas Cage is an American actor, producer and director, having appeared in over 60 films including Raising Arizona , The Rock , Face/Off , Gone in 60 Seconds , Adaptation , National Treasure , Ghost Rider , Bad Lieutenant: Port of Call New Orleans , and...
  
   (January 7, 1964) – movie actor, ex-husband to Patricia (1995–2001)
• Courteney Cox
  Courteney Cox
  Courteney Bass Cox is an American actress, she is best known for her roles as Monica Geller on the NBC sitcom Friends, Gale Weathers in the horror series Scream and as Jules Cobb in the ABC sitcom Cougar Town, for which she earned her first Golden Globe nomination....
  
   (June 15, 1964) – movie and TV actress, married David 1999, separated, 2010. They have one child, Coco.
• Thomas Jane
  Thomas Jane
  Thomas Jane is an American actor known for his roles in the 1999 film Deep Blue Sea, the 2001 TV film 61*, the 2004 film The Punisher and the 2007 Stephen King adaptation The Mist...
  
  – actor, husband to Patricia (2006–2010). They have one child, Harlow. Divorcing as of 2010.