Sinclair Lewis
that was published in 1925. It won the 1926 Pulitzer Prize
for Lewis but he refused to accept it. Lewis was greatly assisted in its preparation by science writer Dr. Paul de Kruif
, who received 25% of the royalties on sales, but Lewis is listed as sole author. Arrowsmith is arguably the earliest major novel to deal with the culture of science
.
Plot
Arrowsmith tells the story of bright and scientifically minded Martin Arrowsmith as he makes his way from a small town in the Midwest to the upper echelons of the scientific community. (He is born in Elk Mills, Winnemac, the same fictional state in which several of Lewis's other novels are set.) Along the way he experiences medical school, private practice
as the only doctor in tiny Wheatsylvania, North Dakota
, various stints as regional health official, and the lure of high-paying hospital jobs. Finally, Arrowsmith is recognized by his former medical school mentor, Max Gottlieb, for a scientific paper he has written and is invited to take a post with a prestigious research institute in New York. The book's climax deals with Dr. Arrowsmith's discovery of a phage that destroys bacteria and his experiences as he faces an outbreak of bubonic plague
on a fictional Caribbean island.
Martin's wife, Leora, is the steadying, sensible, self-abnegating anchor of his life. When Leora dies of the plague that Martin is sent to study and exterminate, he seems to lose all sense of himself and of his principles. The novel comes full circle at the end as Arrowsmith deserts his wealthy second wife and the high-powered directorship of a research institute to pursue his dream of an independent scientific career in backwoods Vermont.
Themes
The book contains considerable social comment on the state and prospects of medicine in the United States in the 1920s. Dr. Arrowsmith is a progressive, even something of a rebel, and often challenges the existing state of things when he finds it wanting.This novel has been inspirational for several generations of pre-medical and medical students. There is much agonizing along the way concerning career and life decisions. While detailing Martin's pursuit of the noble ideals of medical research for the benefit of mankind and of selfless devotion to the care of patients, Lewis throws many less noble temptations and self-deceptions in Martin's path. The attractions of financial security, recognition, even wealth and power distract Arrowsmith from his original plan to follow in the footsteps of his first mentor, Max Gottlieb, a brilliant but abrasive bacteriologist.
In the course of the novel Lewis describes many aspects of medical training, medical practice, scientific research, scientific fraud, medical ethics, public health, and of personal/professional conflicts that are still relevant today. Professional jealousy, institutional pressures, greed, stupidity, and negligence are all satirically depicted, and Martin himself is exasperatingly self-involved. But there is also tireless dedication, and respect for the scientific method and intellectual honesty.
Martin Arrowsmith shares some biographical elements with Félix d'Herelle
, who is identified in the novel as a co-discoverer of the bacteriophage and represented as having beaten Arrowsmith into publication with his results.
Arrowsmith has been compared with The Citadel
by A. J. Cronin
(first published after Arrowsmith in 1937), which also deals with the life experiences of a young idealistic doctor who tries to challenge and improve the existing system of medical practice.
De Kruif is known to have drawn inspiration for locations and characters in Arrowsmith from specific sources. The labwork and experimental process of Max Gottlieb was based on the careers of F. G. Novy and Jacques Loeb
. Loeb and De Kruif both worked at the Rockefeller Institute for Medical Research in New York and Novy was de Kruif's longtime mentor.
Pulitzer Prize
Arrowsmith was awarded the 1926 Pulitzer Prize, but Lewis declined the award. In a letter to the committee, he wrote:
I wish to acknowledge your choice of my novel Arrowsmith for the Pulitzer Prize. That prize I must refuse, and my refusal would be meaningless unless I explained the reasons.
All prizes, like all titles, are dangerous. The seekers for prizes tend to labor not for inherent excellence but for alien rewards; they tend to write this, or timorously to avoid writing that, in order to tickle the prejudices of a haphazard committee. And the Pulitzer Prize for Novels is peculiarly objectionable because the terms of it have been constantly and grievously misrepresented.
Those terms are that the prize shall be given "for the American novel published during the year which shall best present the wholesome atmosphere of American life, and the highest standard of American manners and manhood." This phrase, if it means anything whatsoever, would appear to mean that the appraisal of the novels shall be made not according to their actual literary merit but in obedience to whatever code of Good Form may chance to be popular at the moment."
Film, radio and television adaptations
The book's only theatrically released adaptation, made in 1931, featured Ronald Colman
and Helen Hayes
as Arrowsmith and Leora respectively. It was nominated for four Academy Awards
, including Best Adapted Screenplay
.
Helen Hayes reprised her role as Leora in an hour long adaptation on The Campbell Playhouse
radio program along with Orson Welles
as Arrowsmith. The program aired on February 3, 1939.
In the 1950s and '60s, the book was adapted several times for television
, and condensed versions of the story were produced for such television shows as Kraft Television Theater and DuPont Show of the Month.
A Czech
mini-series was produced in 1999, with Jan Stastny in the titular role and Tereza Brodská as "Leora Tozerova".