Arsthinol
Encyclopedia
Arsthinol is an antiprotozoal agent
. It was synthesized for the first time in 1949 by Ernst A.H. Friedheim by complexation of acetarsol
with 2,3-dimercaptopropanol (British anti-Lewisite) and has been demonstrated to be effective against amoebiasis
and yaws
. It was marketed few years latter by Endo Products (Balarsen, Tablets, 0.1 g).
Among trivalent organoarsenicals, arthinol was considered as very well tolerated . In 2006 it was studied for its antileukemic activity .
Antiprotozoal agent
Antiprotozoal agents is a class of pharmaceuticals used in treatment of protozoan infection.Protozoans have little in common with each other and so agents effective against one pathogen may not be effective against another...
. It was synthesized for the first time in 1949 by Ernst A.H. Friedheim by complexation of acetarsol
Acetarsol
Acetarsol is an anti-infective.It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol . It has been given in suppositories.-References:...
with 2,3-dimercaptopropanol (British anti-Lewisite) and has been demonstrated to be effective against amoebiasis
Amoebiasis
Entamebiasis is a term for the infection more commonly known as amoebiasis.It became the preferred term in MeSH in 1991, but the term amoebiasis is used by the World Health Organization and by those working in the field of amoebiasis research....
and yaws
Yaws
Yaws is a tropical infection of the skin, bones and joints caused by the spirochete bacterium Treponema pallidum pertenue...
. It was marketed few years latter by Endo Products (Balarsen, Tablets, 0.1 g).
Among trivalent organoarsenicals, arthinol was considered as very well tolerated . In 2006 it was studied for its antileukemic activity .