Basolateral Amygdala
Encyclopedia
The Basolateral Amygdala is a major limbic-related region within the brain
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The basolateral amygdala projects heavily to the nucleus accumbens
. The nucleus accumbens is regarded as the limbic-motor interface, in view of these limbic afferent and its somatomotor and autonomic efferent connections. These afferent inputs have been suggested to converge monosynaptically on cells within the accumbens and are hypothesised to play a role in functions such as affective motivational behaviour. In fact there is a robust reciprocal projection between the basolateral amygdala and the hippocampus, synaptic details of which have not been fully investigated.
Bidirectional projections connect the medial prefrontal cortex and basolateral amygdala. This circuit has been implicated to play a role in fear extinction and abnormalities in the projections from the medial prefrontal cortex to the basolateral amygdala have been observed in schizophrenics.
Brain
The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...
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The basolateral amygdala projects heavily to the nucleus accumbens
Nucleus accumbens
The nucleus accumbens , also known as the accumbens nucleus or as the nucleus accumbens septi , is a collection of neurons and forms the main part of the ventral striatum...
. The nucleus accumbens is regarded as the limbic-motor interface, in view of these limbic afferent and its somatomotor and autonomic efferent connections. These afferent inputs have been suggested to converge monosynaptically on cells within the accumbens and are hypothesised to play a role in functions such as affective motivational behaviour. In fact there is a robust reciprocal projection between the basolateral amygdala and the hippocampus, synaptic details of which have not been fully investigated.
Bidirectional projections connect the medial prefrontal cortex and basolateral amygdala. This circuit has been implicated to play a role in fear extinction and abnormalities in the projections from the medial prefrontal cortex to the basolateral amygdala have been observed in schizophrenics.