Bemotrizinol
Encyclopedia
Bemotrizinol is an oil-soluble organic compound
that is added to sunscreen
s to absorb UV
rays. It is marketed as Tinosorb S by BASF
and as Escalol S by International Specialty Products. A recent development is Tinosorb S Aqua, which is bemotrizinol in a PMMA matrix dispersed in water. This makes it possible to add bemotrizinol to the water phase.
Bemotrizinol is a broad-spectrum UV absorber, absorbing UVB as well as UVA rays. It has two absorption peaks, 310 and 340 nm. It is highly photostable. Even after 50 MED
s (minimal erythemal doses), 98.4% remains intact. It helps prevent the photodegradation
of other sunscreen actives like avobenzone
.
Bemotrizinol has strong synergistic
effects on the SPF when formulated with bisoctrizole
, ethylhexyl triazone
or iscotrizinol
. It is the most effective UV absorber available measured by SPF, based on the maximum concentration permitted by European legislation.
Bemotrizinol is not approved by the United States Food and Drug Administration
, but is approved in the European Union since the year 2000 and other parts of the world, including Australia.
Unlike some other organic sunscreen actives, it shows no estrogenic effects in vitro
.
Organic compound
An organic compound is any member of a large class of gaseous, liquid, or solid chemical compounds whose molecules contain carbon. For historical reasons discussed below, a few types of carbon-containing compounds such as carbides, carbonates, simple oxides of carbon, and cyanides, as well as the...
that is added to sunscreen
Sunscreen
Sunblock is a lotion, spray, gel or other topical product that absorbs or reflects some of the sun's ultraviolet radiation on the skin exposed to sunlight and thus helps protect against sunburn...
s to absorb UV
Ultraviolet
Ultraviolet light is electromagnetic radiation with a wavelength shorter than that of visible light, but longer than X-rays, in the range 10 nm to 400 nm, and energies from 3 eV to 124 eV...
rays. It is marketed as Tinosorb S by BASF
BASF
BASF SE is the largest chemical company in the world and is headquartered in Germany. BASF originally stood for Badische Anilin- und Soda-Fabrik . Today, the four letters are a registered trademark and the company is listed on the Frankfurt Stock Exchange, London Stock Exchange, and Zurich Stock...
and as Escalol S by International Specialty Products. A recent development is Tinosorb S Aqua, which is bemotrizinol in a PMMA matrix dispersed in water. This makes it possible to add bemotrizinol to the water phase.
Bemotrizinol is a broad-spectrum UV absorber, absorbing UVB as well as UVA rays. It has two absorption peaks, 310 and 340 nm. It is highly photostable. Even after 50 MED
MED
-Medicine:* Medicine * Medication, often used in the plural "meds"* Title of Medic, the first Physician degree in Argentina* Medical Extrication Device, a device for extricating an injured patient from an accident site, such as the Kendrick Extrication Device* Minimal Erythemal Dose, the minimum...
s (minimal erythemal doses), 98.4% remains intact. It helps prevent the photodegradation
Photodegradation
Photodegradation is degradation of a photodegradable molecule caused by the absorption of photons, particularly those wavelengths found in sunlight, such as infrared radiation, visible light, and ultraviolet light. However, other forms of electromagnetic radiation can cause photodegradation...
of other sunscreen actives like avobenzone
Avobenzone
Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays....
.
Bemotrizinol has strong synergistic
Synergy
Synergy may be defined as two or more things functioning together to produce a result not independently obtainable.The term synergy comes from the Greek word from , , meaning "working together".-Definitions and usages:...
effects on the SPF when formulated with bisoctrizole
Bisoctrizole
Bisoctrizole is a benzotriazole-based organic compound that is added to sunscreens to absorb UV rays....
, ethylhexyl triazone
Ethylhexyl triazone
Ethylhexyl triazone is an organic compound used in sunscreens to absorb UVB radiation. It is marketed as Uvinul T 150 by BASF. Ethylhexyl triazone has an absorption maximum of 314 nm....
or iscotrizinol
Iscotrizinol
Iscotrizinol is an organic compound used in sunscreens to absorb UVA and UVB radiation. It is marketed as Uvasorb HEB by 3V Sigma....
. It is the most effective UV absorber available measured by SPF, based on the maximum concentration permitted by European legislation.
Bemotrizinol is not approved by the United States Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
, but is approved in the European Union since the year 2000 and other parts of the world, including Australia.
Unlike some other organic sunscreen actives, it shows no estrogenic effects in vitro
In vitro
In vitro refers to studies in experimental biology that are conducted using components of an organism that have been isolated from their usual biological context in order to permit a more detailed or more convenient analysis than can be done with whole organisms. Colloquially, these experiments...
.