Beta-Naphthoflavone
Encyclopedia
beta-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor
and as such is an inducer of such detoxification enzymes as cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases
(UGTs). β-Naphthoflavone is a putative chemopreventive agent.
Aryl hydrocarbon receptor
The Aryl hydrocarbon receptor is a member of the family of basic-helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones...
and as such is an inducer of such detoxification enzymes as cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases
Glucuronosyltransferase
Uridine 5'-diphospho-glucuronosyltransferase is a glycosyltransferase that catalyzes addition of the glycosyl group from a UTP-sugar to a small hydrophobic molecule.This is glucuronidation reaction.Alternative names:...
(UGTs). β-Naphthoflavone is a putative chemopreventive agent.