CHD1L
Encyclopedia
Chromodomain-helicase-DNA-binding protein 1-like is an enzyme
that in humans is encoded by the CHD1L gene
. It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription.
With 1q21.1 deletion syndrome
a disturbance occurs, which leads to increased DNA breaks. The role of CHD1L is similar to that of helicase
with the Werner syndrome
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the CHD1L gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription.
Related gene problems
- 1q21.1 deletion syndrome1q21.1 deletion syndrome1q21.1 deletion syndrome or 1q21.1 microdeletion is a rare aberration of chromosome 1. , the international rare chromosome disorder group, has 48 genetically confirmed registered cases of this deletion worldwide ....
- 1q21.1 duplication syndrome1q21.1 duplication syndrome1q21.1 duplication syndrome or 1q21.1 microduplication is a rare aberration of chromosome 1. , the international rare chromosome disorder group, has 38 genetically confirmed registered cases of this duplication worldwide ....
With 1q21.1 deletion syndrome
1q21.1 deletion syndrome
1q21.1 deletion syndrome or 1q21.1 microdeletion is a rare aberration of chromosome 1. , the international rare chromosome disorder group, has 48 genetically confirmed registered cases of this deletion worldwide ....
a disturbance occurs, which leads to increased DNA breaks. The role of CHD1L is similar to that of helicase
Helicase
Helicases are a class of enzymes vital to all living organisms. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone, separating two annealed nucleic acid strands using energy derived from ATP hydrolysis.-Function:Many cellular processes Helicases are a...
with the Werner syndrome
Werner syndrome
Werner syndrome is a very rare, autosomal recessive disorder characterized by the appearance of premature aging....