CUL3
Encyclopedia
Cullin-3 is a protein
that in humans is encoded by the CUL3 gene
.
with KLHL12
, CAND1
, KEAP1
, DCUN1D1
and Cyclin E1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the CUL3 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
CUL3 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with KLHL12
KLHL12
Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene.-Interactions:KLHL12 has been shown to interact with RIT1 and CUL3.-Further reading:...
, CAND1
CAND1
Cullin-associated NEDD8-dissociated protein 1 is a protein that in humans is encoded by the CAND1 gene.-Interactions:CAND1 has been shown to interact with CUL4A, CUL4B, RBX1, CUL1, DCUN1D1, CUL3 and CUL2.-Further reading:...
, KEAP1
KEAP1
Kelch-like ECH-associated protein 1 is a protein that in humans is encoded by the Keap1 gene.-Structure:Keap1 has four discrete protein domains. The Broad complex, Tramtrack and Bric-à-Brac domain contains the Cys151 residue, which is important in stress sensing...
, DCUN1D1
DCUN1D1
DCN1-like protein 1 is a protein that in humans is encoded by the DCUN1D1 gene.-Interactions:DCUN1D1 has been shown to interact with CAND1, RBX1, CUL1, CUL3 and CUL2.-Further reading:...
and Cyclin E1
Cyclin E1
G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene.-Interactions:Cyclin E1 has been shown to interact with Retinoblastoma-like protein 2, Cdk1, CDC25A, Cyclin-dependent kinase 2, SMARCA4, CDKN1B, HERC5, CUL3 and P21....
.