CY-208,243
Encyclopedia
CY-208,243 is a drug which acts as a dopamine agonist
selective for the D1
subtype. Unlike most D1-selective agonists, it shows efficacy in animal models of Parkinson's disease
.
Dopamine agonist
A dopamine agonist is a compound that activates dopamine receptors in the absence of dopamine. Dopamine agonists activate signaling pathways through the dopamine receptor and trimeric G-proteins, ultimately leading to changes in gene transcription.-Uses:...
selective for the D1
Dopamine receptor D1
Dopamine receptor D1, also known as DRD1, is a protein that in humans is encoded by the DRD1 gene.- Function :This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein-coupled receptor stimulates...
subtype. Unlike most D1-selective agonists, it shows efficacy in animal models of Parkinson's disease
Parkinson's disease
Parkinson's disease is a degenerative disorder of the central nervous system...
.