Charles Pravaz
Encyclopedia
Charles Gabriel Pravaz was a French
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...

 orthopedic surgeon
Surgeon
In medicine, a surgeon is a specialist in surgery. Surgery is a broad category of invasive medical treatment that involves the cutting of a body, whether human or animal, for a specific reason such as the removal of diseased tissue or to repair a tear or breakage...

 and inventor of the hypodermic syringe
Syringe
A syringe is a simple pump consisting of a plunger that fits tightly in a tube. The plunger can be pulled and pushed along inside a cylindrical tube , allowing the syringe to take in and expel a liquid or gas through an orifice at the open end of the tube...

.

While the concept dated to Galen
Galen
Aelius Galenus or Claudius Galenus , better known as Galen of Pergamon , was a prominent Roman physician, surgeon and philosopher...

, the modern syringe is thought to have originated in Fifteenth Century Italy, although it took several centuries for the device to be developed. In 1657, experiments were conducted on syringe-like devices by Englishmen Christopher Wren
Christopher Wren
Sir Christopher Wren FRS is one of the most highly acclaimed English architects in history.He used to be accorded responsibility for rebuilding 51 churches in the City of London after the Great Fire in 1666, including his masterpiece, St. Paul's Cathedral, on Ludgate Hill, completed in 1710...

 and Robert Boyle
Robert Boyle
Robert Boyle FRS was a 17th century natural philosopher, chemist, physicist, and inventor, also noted for his writings in theology. He has been variously described as English, Irish, or Anglo-Irish, his father having come to Ireland from England during the time of the English plantations of...

, while French physician Dominique Anel
Dominique Anel
Dominique Anel , French surgeon, was born at Toulouse about 1679.After studying at Montpellier and Paris, he served as surgeon-major in the French army in Alsace; then after two years at Vienna he went to Italy and served in the Austrian army. In 1710 he was teaching surgery in Rouen, whence he...

 created the modern pump syringe as a device to clean wounds using suction.

In all these cases, it was impossible to perform injections without an incision until Irish
Ireland
Ireland is an island to the northwest of continental Europe. It is the third-largest island in Europe and the twentieth-largest island on Earth...

 physician Francis Rynd invented the hollow needle
Hypodermic needle
A hypodermic needle is a hollow needle commonly used with a syringe to inject substances into the body or extract fluids from it...

 in 1844. Wanting to inject of iron perchloride coagulant
Coagulant
Coagulant can refer to:* flocculation* coagulation agent...

 into an aneurysm
Aneurysm
An aneurysm or aneurism is a localized, blood-filled balloon-like bulge in the wall of a blood vessel. Aneurysms can commonly occur in arteries at the base of the brain and an aortic aneurysm occurs in the main artery carrying blood from the left ventricle of the heart...

, Pravaz adapted Rynd's needle, rather than using the usual suction tube. Measuring 3 cm (1.18 in) long and 5 mm (0.2 in) in diameter, the syringe was entirely in silver, made by Établissements Charrière, and operated by a screw (rather than the plunger familiar today) to control the amount of substance injected.

Pravaz did little development of the invention, and it would be another French surgeon, L. J. Béhier, who would make Pravaz's invention known across Europe. It thus initiated the science of sclerotherapy
Sclerotherapy
Sclerotherapy is a procedure used to treat blood vessels or blood vessel malformations and also those of the lymphatic system. A medicine is injected into the vessels, which makes them shrink. It is used for children and young adults with vascular or lymphatic malformations...

 and the treatment of varicose veins
Varicose veins
Varicose veins are veins that have become enlarged and tortuous. The term commonly refers to the veins on the leg, although varicose veins can occur elsewhere. Veins have leaflet valves to prevent blood from flowing backwards . Leg muscles pump the veins to return blood to the heart, against the...

 and other varices
Varices
Varices may refer to:In lower extremities* Varicose veins, large tortuous veins usually found on legsIn the digestive system* Sublingual varices* Esophageal varices, also known as Oesophageal varices* Gastric varices* Intestinal varices...

.

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