Children's Cancer Study Group
Encyclopedia
The Children's Cancer Study Group (CCG) was a U.S.
and Canadian
clinical trial
cooperative group created with the mission of studying childhood cancers. The CCG was originally known as Cancer and Leukemia Group A (CALGA) when it was associated with CALGB. In 2000, the CCG merged with several other pediatric cooperative groups to form the Children's Oncology Group
(COG). This merger has seen its fair share of problems, especially with regard to integrating the various databases associated with each individual cooperative group. One such initiative to consolidate these databases involves caBIG
or cancer BIG, which is guided and supported by the National Cancer Institute
(NCI) in Bethesda, Maryland
.
(QARC). As mandated by the National Cancer Institute
(NCI), every radiotherapy (RT) department participating in an CCG study submits their data to QARC for review. QARC is located in Lincoln, Rhode Island
and reviews thousands of RT cases per year. The center was founded in 1977 as a not-for-profit health care organization designed to provide quality assurance for CALGB studies. Radiotherapy data from around one-thousand hospitals in both the United States
and abroad is reviewed and archived at QARC.
Another center for quality assurance is the Radiological Physics Center
(RPC) in Houston, Texas
. The primary responsibility of the RPC is to assure the National Cancer Institute
(NCI) and its cooperative groups like CCG that all participating institutions are following the basic guidelines regarding the physics-related aspects of radiotherapy. Established in 1968, the RPC has consistently received funding from the NCI in order to perform the aforementioned mission.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
and Canadian
Canada
Canada is a North American country consisting of ten provinces and three territories. Located in the northern part of the continent, it extends from the Atlantic Ocean in the east to the Pacific Ocean in the west, and northward into the Arctic Ocean...
clinical trial
Clinical trial
Clinical trials are a set of procedures in medical research and drug development that are conducted to allow safety and efficacy data to be collected for health interventions...
cooperative group created with the mission of studying childhood cancers. The CCG was originally known as Cancer and Leukemia Group A (CALGA) when it was associated with CALGB. In 2000, the CCG merged with several other pediatric cooperative groups to form the Children's Oncology Group
Children's Oncology Group
The Children’s Oncology Group , a National Cancer Institute supported clinical trials group, is the world’s largest organization devoted exclusively to childhood and adolescent cancer research...
(COG). This merger has seen its fair share of problems, especially with regard to integrating the various databases associated with each individual cooperative group. One such initiative to consolidate these databases involves caBIG
CaBIG
The cancer Biomedical Informatics Grid is an open source, open access information network with the mission of enabling secure data exchange throughout the cancer community...
or cancer BIG, which is guided and supported by the National Cancer Institute
National Cancer Institute
The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...
(NCI) in Bethesda, Maryland
Bethesda, Maryland
Bethesda is a census designated place in southern Montgomery County, Maryland, United States, just northwest of Washington, D.C. It takes its name from a local church, the Bethesda Meeting House , which in turn took its name from Jerusalem's Pool of Bethesda...
.
Quality Assurance
The Children's Cancer Study Group has all of its protocol-driven cases reviewed at the Quality Assurance Review CenterQuality Assurance Review Center
The Quality Assurance Review Center is a research program within the University of Massachusetts Medical School that provides radiotherapy quality assurance , diagnostic imaging data management, and clinical research support...
(QARC). As mandated by the National Cancer Institute
National Cancer Institute
The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...
(NCI), every radiotherapy (RT) department participating in an CCG study submits their data to QARC for review. QARC is located in Lincoln, Rhode Island
Lincoln, Rhode Island
Lincoln is a town in Providence County, Rhode Island, United States. The population was 21,105 at the 2010 census. Lincoln is located in northeastern Rhode Island, north of Providence....
and reviews thousands of RT cases per year. The center was founded in 1977 as a not-for-profit health care organization designed to provide quality assurance for CALGB studies. Radiotherapy data from around one-thousand hospitals in both the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
and abroad is reviewed and archived at QARC.
Another center for quality assurance is the Radiological Physics Center
Radiological Physics Center
-Mission statement:The mission of the Radiological Physics Center is to assure NCI and the Cooperative Groups that institutions participating in clinical trials deliver prescribed radiation doses that are clinically comparable and consistent....
(RPC) in Houston, Texas
Houston, Texas
Houston is the fourth-largest city in the United States, and the largest city in the state of Texas. According to the 2010 U.S. Census, the city had a population of 2.1 million people within an area of . Houston is the seat of Harris County and the economic center of , which is the ...
. The primary responsibility of the RPC is to assure the National Cancer Institute
National Cancer Institute
The National Cancer Institute is part of the National Institutes of Health , which is one of 11 agencies that are part of the U.S. Department of Health and Human Services. The NCI coordinates the U.S...
(NCI) and its cooperative groups like CCG that all participating institutions are following the basic guidelines regarding the physics-related aspects of radiotherapy. Established in 1968, the RPC has consistently received funding from the NCI in order to perform the aforementioned mission.