Chlorisondamine
Encyclopedia
Chlorisondamine is a nicotinic acetylcholine receptor
antagonist
that produces both neuronal and ganglionic blockade.
Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin
and other associated glycolipid
s.
Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction...
antagonist
Nicotinic antagonist
A nicotinic antagonist is a type of anticholinergic that inhibits the action at nicotinic acetylcholine receptors. These compounds are mainly used for peripheral muscle paralysis in surgery, but some centrally acting compounds such as bupropion, mecamylamine, and 18-methoxycoronaridine block...
that produces both neuronal and ganglionic blockade.
Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin
Sphingomyelin
Sphingomyelin is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath that surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide...
and other associated glycolipid
Glycolipid
Glycolipids are lipids with a carbohydrate attached. Their role is to provide energy and also serve as markers for cellular recognition.-Metabolism:...
s.