Choroid plexus papilloma
Encyclopedia
A Choroid plexus papilloma (CPP) is a rare, slow-growing, histologically benign intracranial neoplasm or tumor
that is commonly located in the ventricular system
of the choroid plexus
. It may obstruct the cerebrospinal fluid
flow, causing increased intracranial pressure
.
. They may be created by epithelial cells of the choroid plexus
.
are present in 91% of patients, with vomiting
, homonymous visual field defects and headache
being the most common symptoms.
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...
that is commonly located in the ventricular system
Ventricular system
The ventricular system is a set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord.-Components:The system comprises four ventricles:* right and left lateral ventricles* third ventricle...
of the choroid plexus
Choroid plexus
The choroid plexus is a structure in the ventricles of the brain where cerebrospinal fluid is produced...
. It may obstruct the cerebrospinal fluid
Cerebrospinal fluid
Cerebrospinal fluid , Liquor cerebrospinalis, is a clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord...
flow, causing increased intracranial pressure
Intracranial pressure
Intracranial pressure is the pressure inside the skull and thus in the brain tissue and cerebrospinal fluid . The body has various mechanisms by which it keeps the ICP stable, with CSF pressures varying by about 1 mmHg in normal adults through shifts in production and absorption of CSF...
.
Pathophysiology
The tumor is neuroectodermal in origin and similar in structure to a normal choroid plexusChoroid plexus
The choroid plexus is a structure in the ventricles of the brain where cerebrospinal fluid is produced...
. They may be created by epithelial cells of the choroid plexus
Choroid plexus
The choroid plexus is a structure in the ventricles of the brain where cerebrospinal fluid is produced...
.
Frequency and age affected
Internationally tumors of the choroid plexus are rare, accounting for 0.4-0.6% of all intracranial neoplasms. It most commonly affects young children under the age of 5 with a mean patient age of 5.2 years.Signs and symptoms
Signs of the tumor resulting from increased intracranial pressureIntracranial pressure
Intracranial pressure is the pressure inside the skull and thus in the brain tissue and cerebrospinal fluid . The body has various mechanisms by which it keeps the ICP stable, with CSF pressures varying by about 1 mmHg in normal adults through shifts in production and absorption of CSF...
are present in 91% of patients, with vomiting
Vomiting
Vomiting is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose...
, homonymous visual field defects and headache
Headache
A headache or cephalalgia is pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions of the head and neck. The brain tissue itself is not sensitive to pain because it lacks pain receptors. Rather, the pain is caused by disturbance of the...
being the most common symptoms.
Surgical treatment
Choroid plexus papillomas are benign tumors that are usually cured by surgery; malignant progression has been rarely reported.External links
- Choroid Plexus Papilloma MRI, CT, and pathology images from MedPix