Clostridium sporogenes
Encyclopedia
Clostridium sporogenes is the name given to strains of Clostridium botulinum
that do not produce botulinum neurotoxins. Like other strains of C. botulinum, it is an anaerobic
Gram-positive
, rod-shaped bacterium that produces oval, subterminal endospores and is commonly found in soil
. It is being investigated as a way to deliver cancer-treating drugs to tumours in patients.
C. sporogenes is often used as a surrogate for C. botulinum when testing the efficacy of commercial sterilisation
.
Clostridium botulinum
Clostridium botulinum is a Gram-positive, rod-shaped bacterium that produces several toxins. The best known are its neurotoxins, subdivided in types A-G, that cause the flaccid muscular paralysis seen in botulism. It is also the main paralytic agent in botox. C. botulinum is an anaerobic...
that do not produce botulinum neurotoxins. Like other strains of C. botulinum, it is an anaerobic
Anaerobic organism
An anaerobic organism or anaerobe is any organism that does not require oxygen for growth. It could possibly react negatively and may even die if oxygen is present...
Gram-positive
Gram-positive
Gram-positive bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain and appearing red or pink...
, rod-shaped bacterium that produces oval, subterminal endospores and is commonly found in soil
Soil
Soil is a natural body consisting of layers of mineral constituents of variable thicknesses, which differ from the parent materials in their morphological, physical, chemical, and mineralogical characteristics...
. It is being investigated as a way to deliver cancer-treating drugs to tumours in patients.
C. sporogenes is often used as a surrogate for C. botulinum when testing the efficacy of commercial sterilisation
Sterilization (microbiology)
Sterilization is a term referring to any process that eliminates or kills all forms of microbial life, including transmissible agents present on a surface, contained in a fluid, in medication, or in a compound such as biological culture media...
.