Cobamamide
Encyclopedia
Cobamamide which is also known as adenosylcobalamin and dibencozide, is, along with methylcobalamin (MeCbl), one of the active forms of vitamin B12
. As a nutritional supplement, it is available in tabletted form, but, (unlike cyanocobalamin
, methylcobalamin, and hydroxocobalamin
), it is not available in injectable form.
An enzyme
that uses adenosylcobalamin as a cofactor
is methylmalonyl-CoA mutase
(MCM).
Vitamin B12
Vitamin B12, vitamin B12 or vitamin B-12, also called cobalamin, is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins...
. As a nutritional supplement, it is available in tabletted form, but, (unlike cyanocobalamin
Cyanocobalamin
Cyanocobalamin is an especially common vitamer of the vitamin B12 family. It is the most famous vitamer of the family, because it is, in chemical terms, the most air-stable...
, methylcobalamin, and hydroxocobalamin
Hydroxocobalamin
Hydroxocobalamin is a natural form, or vitamer, of vitamin B12, a basic member of the cobalamin family of compounds. Hydroxocobalamin is the form of vitamin B12 produced by many bacteria which are used to produce the vitamin commercially. Like other forms of vitamin B12, hydroxocobalamin has an...
), it is not available in injectable form.
An enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that uses adenosylcobalamin as a cofactor
Cofactor (biochemistry)
A cofactor is a non-protein chemical compound that is bound to a protein and is required for the protein's biological activity. These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations....
is methylmalonyl-CoA mutase
Methylmalonyl-CoA mutase
Methylmalonyl Coenzyme A mutase, also known as MCM is an enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA and it is involved in key metabolic pathways...
(MCM).