Collaborative Drug Discovery
Encyclopedia
Collaborative Drug Discovery (CDD) is a software company founded in 2004 as a spin-out of Eli Lilly
by Barry Bunin, PhD. CDD offers a web-based
database solution for managing drug discovery
data, primarily around small molecules and associated bio-assay data.
, who in 2008 awarded CDD with a two million dollar grant being used to support researchers combating Tuberculosis
.
In 2010, GlaxoSmithKline
released 13,471 molecules screened for activity against Malaria
to the public. These molecules and their associated screening data are available via CDD Public, as well in as the National Library of Medicine's
PubChem
and the European Bioinformatics Institute's
ChEMBL
database. This data has served as the basis for several cheminformatics analyses
In February 2011 CDD began participating in the collaborative MM4TB project led by Professor Stewart Cole and including participants from AstraZeneca and Sanofi Aventis
Eli Lilly and Company
Eli Lilly and Company is a global pharmaceutical company. Eli Lilly's global headquarters is located in Indianapolis, Indiana, in the United States...
by Barry Bunin, PhD. CDD offers a web-based
Web application
A web application is an application that is accessed over a network such as the Internet or an intranet. The term may also mean a computer software application that is coded in a browser-supported language and reliant on a common web browser to render the application executable.Web applications are...
database solution for managing drug discovery
Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered or designed.In the past most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery...
data, primarily around small molecules and associated bio-assay data.
Products
- CDD Vault - allows scientists to maintain a private and secure collection of their data.
- CDD Collaborate - individual research groups can securely share subsets of data between Vaults.
- CDD Public - a free database for fostering open collaboration containing over 3 million molecules accessible to everyone in the drug discovery community at large.
Collaborations
The capability for inter-group collaboration attracted attention from the Bill & Melinda Gates FoundationBill & Melinda Gates Foundation
The Bill & Melinda Gates Foundation is the largest transparently operated private foundation in the world, founded by Bill and Melinda Gates. It is "driven by the interests and passions of the Gates family"...
, who in 2008 awarded CDD with a two million dollar grant being used to support researchers combating Tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...
.
In 2010, GlaxoSmithKline
GlaxoSmithKline
GlaxoSmithKline plc is a global pharmaceutical, biologics, vaccines and consumer healthcare company headquartered in London, United Kingdom...
released 13,471 molecules screened for activity against Malaria
Malaria
Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases...
to the public. These molecules and their associated screening data are available via CDD Public, as well in as the National Library of Medicine's
United States National Library of Medicine
The United States National Library of Medicine , operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is a division of the National Institutes of Health...
PubChem
PubChem
PubChem is a database of chemical molecules and their activities against biological assays. The system is maintained by the National Center for Biotechnology Information , a component of the National Library of Medicine, which is part of the United States National Institutes of Health . PubChem can...
and the European Bioinformatics Institute's
European Bioinformatics Institute
The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...
ChEMBL
ChEMBL
ChEMBL or ChEMBLdb is a manually curated chemical database of bioactive molecules with drug-like properties.It is maintained by the European Bioinformatics Institute , based on the Wellcome Trust Genome Campus, Hinxton, UK. The database, originally known as StARlite, was developed by a...
database. This data has served as the basis for several cheminformatics analyses
In February 2011 CDD began participating in the collaborative MM4TB project led by Professor Stewart Cole and including participants from AstraZeneca and Sanofi Aventis