Comby sign
Encyclopedia
The Comby sign is a clinical sign
of early measles
in which thin, whitish patches are seen on the gums
and buccal mucosa due to desquamation
of epithelial cells
.
The sign is named after Jules Comby
.
Medical sign
A medical sign is an objective indication of some medical fact or characteristic that may be detected by a physician during a physical examination of a patient....
of early measles
Measles
Measles, also known as rubeola or morbilli, is an infection of the respiratory system caused by a virus, specifically a paramyxovirus of the genus Morbillivirus. Morbilliviruses, like other paramyxoviruses, are enveloped, single-stranded, negative-sense RNA viruses...
in which thin, whitish patches are seen on the gums
Gingiva
The gingiva , or gums, consists of the mucosal tissue that lies over the mandible and maxilla inside the mouth.-General description:...
and buccal mucosa due to desquamation
Desquamation
Desquamation , also called skin peeling, is the shedding of the outermost membrane or layer of a tissue, such as the skin.-Skin:Normal, nonpathologic desquamation of the skin occurs when keratinocytes, after moving apically over about 14 days, are individually shed unnoticeably...
of epithelial cells
Epithelium
Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective...
.
The sign is named after Jules Comby
Jules Comby
Jules Comby was a French pediatrician. With Antoine Marfan and Jacques-Joseph Grancher , he published the influential Traité des maladies de l’enfance...
.