Cumulina
Encyclopedia
Cumulina a mouse, was the first animal cloned from adult cells that survived to adulthood. She was cloned using the Honolulu technique developed by the Ryuzo Yanagimachi
research group, 'Team Yana', at the former campus of the John A. Burns School of Medicine
located at the University of Hawai'i at Mānoa
. She was a brown Mus musculus or common house mouse. Cumulina was named after the cumulus cells surrounding the developing ovarian follicle in mice. Nuclei from these cells were put into egg cell devoid of their original nuclei in the Honolulu cloning technique. All other mice produced by the Yanagimachi lab are just known by a number.
Cumulina was able to produce two healthy litters. She was retired after the second.
Cumulina's preserved remains can be visited at the Institute for Biogenesis Research, a part of the John A. Burns School of Medicine laboratory, in Honolulu, Hawaii.
Some of her descendants have been displayed at the Bishop Museum
and the Museum of Science and Industry
in Chicago, Illinois.
Ryuzo Yanagimachi
has made major contributions in understanding the process and mechanism of mammalian fertilization. He is a pioneer of assisted fertilization technologies such as in vitro fertilization and direct sperm injection into egg which are widely used today in human infertility clinics throughout the world...
research group, 'Team Yana', at the former campus of the John A. Burns School of Medicine
John A. Burns School of Medicine
The John A. Burns School of Medicine is a public, co-educational institution of the University of Hawaii at Mānoa in Honolulu, Hawaii and is one of the leading medical education institutions in the United States. In 1992, Harvard University identified the John A...
located at the University of Hawai'i at Mānoa
University of Hawaii at Manoa
The University of Hawaii at Mānoa is a public, co-educational university and is the flagship campus of the greater University of Hawaii system...
. She was a brown Mus musculus or common house mouse. Cumulina was named after the cumulus cells surrounding the developing ovarian follicle in mice. Nuclei from these cells were put into egg cell devoid of their original nuclei in the Honolulu cloning technique. All other mice produced by the Yanagimachi lab are just known by a number.
Cumulina was able to produce two healthy litters. She was retired after the second.
Cumulina's preserved remains can be visited at the Institute for Biogenesis Research, a part of the John A. Burns School of Medicine laboratory, in Honolulu, Hawaii.
Some of her descendants have been displayed at the Bishop Museum
Bishop Museum
The Bishop Museum , is a museum of history and science in the historic Kalihi district of Honolulu on the Hawaiian island of O'ahu...
and the Museum of Science and Industry
Museum of Science and Industry (Chicago)
The Museum of Science and Industry is located in Chicago, Illinois, USA in Jackson Park, in the Hyde Park neighborhood adjacent to Lake Michigan. It is housed in the former Palace of Fine Arts from the 1893 World's Columbian Exposition...
in Chicago, Illinois.