Cyanuric fluoride
Overview
 
Cyanuric fluoride or 2,4,6-trifluoro-1,3,5-triazine is a chemical compound
Chemical compound
A chemical compound is a pure chemical substance consisting of two or more different chemical elements that can be separated into simpler substances by chemical reactions. Chemical compounds have a unique and defined chemical structure; they consist of a fixed ratio of atoms that are held together...

 with the formula
Chemical formula
A chemical formula or molecular formula is a way of expressing information about the atoms that constitute a particular chemical compound....

 (CNF)3. It is a
colourless, pungent liquid. It has been used as a precursor for fibre-reactive dyes
Reactive dye
In a reactive dye a chromophore contains a substituent that is activated and allowed to directly react to the surface of the substrate. Reactive dyes have good fastness properties owing to the bonding that occurs during dyeing....

, as a specific reagent for tyrosine
Tyrosine
Tyrosine or 4-hydroxyphenylalanine, is one of the 22 amino acids that are used by cells to synthesize proteins. Its codons are UAC and UAU. It is a non-essential amino acid with a polar side group...

 residues in enzymes, and as a fluorinating agent.
Cyanuric fluoride is prepared by fluorinating cyanuric chloride
Cyanuric chloride
Cyanuric chloride is the inorganic compound with the formula 3. This colorless solid is the chlorinated derivative of 1,3,5-triazine. It is the trimer of cyanogen chloride...

. The fluorinating agent may be SbF3Cl2, KSO2F, or NaF
Sodium fluoride
Sodium fluoride is an inorganic chemical compound with the formula NaF. A colorless solid, it is a source of the fluoride ion in diverse applications. Sodium fluoride is less expensive and less hygroscopic than the related salt potassium fluoride....

.

Cyanuric fluoride is used for the mild and direct conversion of carboxylic acid
Carboxylic acid
Carboxylic acids are organic acids characterized by the presence of at least one carboxyl group. The general formula of a carboxylic acid is R-COOH, where R is some monovalent functional group...

s to acyl fluorides
Acyl halide
An acyl halide is a chemical compound derived from an oxoacid by replacing a hydroxyl group with a halide group....

:


Other fluorinating methods are less direct and may be incompatible with some functional group
Functional group
In organic chemistry, functional groups are specific groups of atoms within molecules that are responsible for the characteristic chemical reactions of those molecules. The same functional group will undergo the same or similar chemical reaction regardless of the size of the molecule it is a part of...

s.

Cyanuric fluoride hydrolyses
Hydrolysis
Hydrolysis is a chemical reaction during which molecules of water are split into hydrogen cations and hydroxide anions in the process of a chemical mechanism. It is the type of reaction that is used to break down certain polymers, especially those made by condensation polymerization...

 easily to cyanuric acid
Cyanuric acid
Cyanuric acid or 1,3,5-triazine-2,4,6-triol is a chemical compound with the formula 3. Like many industrially useful chemicals, this triazine has many synonyms. This white, odorless solid finds use as a precursor or a component of bleaches, disinfectants, and herbicides...

 and it reacts more readily with nucleophile
Nucleophile
A nucleophile is a species that donates an electron-pair to an electrophile to form a chemical bond in a reaction. All molecules or ions with a free pair of electrons can act as nucleophiles. Because nucleophiles donate electrons, they are by definition Lewis bases.Nucleophilic describes the...

s than cyanuric chloride.
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