DOV Pharmaceutical
Encyclopedia
DOV Pharmaceutical, a biotechnology
company, focuses on therapies primarily for central nervous system conditions. The firm's lead drug candidate, Indiplon
, is said to treat insomnia
. Indiplon targets the same subset of neurotransmitter receptors affected by Valium and Xanax
, but with more specificity to avoid the side effects associated with those drugs. DOV Pharmaceutical, Neurocrine Biosciences
, and Pfizer
are working on the candidate. Other candidates in DOV's pipeline target depression
and angina, pain
, anxiety
, high blood pressure, and other disorders.
Biotechnology
Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. Biotechnology also utilizes these products for manufacturing purpose...
company, focuses on therapies primarily for central nervous system conditions. The firm's lead drug candidate, Indiplon
Indiplon
Indiplon is a nonbenzodiazepine, hypnotic sedative being developed in 2 formulations - an immediate release product for sleep onset and a modified-release version for sleep maintenance.- Mode of action :...
, is said to treat insomnia
Insomnia
Insomnia is most often defined by an individual's report of sleeping difficulties. While the term is sometimes used in sleep literature to describe a disorder demonstrated by polysomnographic evidence of disturbed sleep, insomnia is often defined as a positive response to either of two questions:...
. Indiplon targets the same subset of neurotransmitter receptors affected by Valium and Xanax
Alprazolam
Alprazolam is a short-acting anxiolytic of the benzodiazepine class of psychoactive drugs. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA gamma-amino-butyric acid receptor...
, but with more specificity to avoid the side effects associated with those drugs. DOV Pharmaceutical, Neurocrine Biosciences
Neurocrine Biosciences
Neurocrine Biosciences is a biopharmaceutical company founded in 1992 and located in San Diego, California. The company tooks its name from the original focus on therapies for neurological and endocrine diseases and disorders....
, and Pfizer
Pfizer
Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...
are working on the candidate. Other candidates in DOV's pipeline target depression
Clinical depression
Major depressive disorder is a mental disorder characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities...
and angina, pain
Pain
Pain is an unpleasant sensation often caused by intense or damaging stimuli such as stubbing a toe, burning a finger, putting iodine on a cut, and bumping the "funny bone."...
, anxiety
Anxiety
Anxiety is a psychological and physiological state characterized by somatic, emotional, cognitive, and behavioral components. The root meaning of the word anxiety is 'to vex or trouble'; in either presence or absence of psychological stress, anxiety can create feelings of fear, worry, uneasiness,...
, high blood pressure, and other disorders.