Daniel Kraft
Encyclopedia
Daniel Kraft, M.D. is an NIH funded faculty member affiliated with Stanford. He was on clinical faculty with the UCSF pediatric bone marrow transplantation service and serves as the medicine track chair for Singularity University
where he is also executive director for the FutureMed executive program.
Daniel is the founder of StemCor Systems and founder and consulting chief medical officer for RegenMed Systems, a clinical-stage medical device company that develops tools to enable regenerative stem cell therapies. He is the inventor of the MarrowMiner, a minimally invasive device for the harvest of bone marrow derived stem and progenitor cells. This device is being commercialized by Hospira Inc. for use in bone marrow transplantation and by RegenMed Systems for use in regenerative medicine.
Dr. Kraft received a degree in Biochemistry from Brown University
and his M.D. from the Stanford University School of Medicine
. He completed the Harvard combined residency in Internal Medicine and Pediatrics at the Massachusetts General Hospital
and the Boston Children's Hospital, before returning to Stanford for clinical fellowship training in hematology/oncology and bone marrow transplantation and a post-doctoral fellowship with Dr. Irving Weissman
. Dr. Kraft is board certified in both Pediatrics and Internal Medicine.
In addition to his research and scientific papers, Dr. Kraft has spoken publicly on, performed research into, and consulted on: health data, health statistics, personalized medicine, heath decision making, the future of medicine, and emerging medical technologies.
. As a Howard Hughes Medical Institute
medical student research fellow at Stanford, he discovered at novel population of developing T-cells, which play a role in HIV infection. His research focuses extensively on stem cell biology, immunology, and regenerative medicine.
Dr. Kraft's research focuses on: stem cell biology and regenerative medicine, stem cell derived immunotherapies for cancer, bioengineering, the hematopoietic stem cell niche in murine and human systems, human T-cell differentiation, and humanized animal models. Dr. Kraft's clinical work focuses on: bone marrow / hematopoietic Stem cell transplantation for malignant and non-malignant diseases in adults & children, medical devices to enable stem cell based regenerative medicine, including marrow derived stem cell harvesting, processing and delivery.
Dr. Kraft built the first Internet-based alphanumeric paging system at the Stanford hospitals to facilitate communication between clinical staff, and later for elements of Stanford internal medicine and bone marrow transplant service.
In addition to his research at and in connection with Stanford University, Dr. Kraft has performed research into and consulting on health data, health statistics, personalized medicine and heath decision making, including work as an adviser to CollabRx (personalized oncology), Wellsphere (health and wellness) (acquired by HealthCentral
), Cepheid (point of care diagnostics), and to the X-Prize Foundation.
and Nature
. He has lectured extensively on stem cell biology and regenerative medicine, and has authored several book chapters.
Publications include the following articles: Endochondral ossification is required for haematopoietic stem-cell niche formation, Scientific Paper: Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches, Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction, Efficacy of a Novel, Minimally Invasive Bone Marrow Harvesting Device in Pre-Clinical Evaluation and First Human Use, Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction, Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease, Hematopoietic Stem Cells- Basic Science and Clinical Applications, Detection and characterization of cellular immune responses using peptide-MHC microarrays, Venoconstrictive thigh cuffs impede fluid shifts during simulated microgravity, HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo, Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate, and Inhibition of allergic reactions with monoclonal antibody to the high affinity IgE receptor.
He is a Major in the Air National Guard
and serves as flight surgeon, originally with an F-15
squadron in the Massachusetts Air National Guard
and currently with an F-16 squadron in the 144th Fighter Wing
, California Air National Guard
, with whom he has deployed to Nicaragua
and Saudi Arabia
.
Dr. Kraft is a graduate of the International Space University
. Additionally, he has published physiological research at NASA-Ames
and JSC
, and was a finalist for astronaut selection.
and 2009 & 2011 TEDMED conferences, Singularity University, the Web 2.0 summit, and the 2009 Keynote Address at the USC Body Computing Conference.
Talks and panel discussions include: "TEDTalk - Medicine's Future", "Hype, Hope & Reality in Stem Cells and Regenerative Medicine", "The Future of Medicine", "The Future of Health", and "The Convergence of Life Sciences, Medicine and Exponentially Advancing Life Technologies." and a TED presentation on the Marrow Miner, a minimally invasive bone marrow and adult stem cell harvesting device invented by Dr. Kraft.
Dr. Kraft is a founder of StemCor Systems.
Dr. Kraft serves as faculty track chair for Medicine & Neuroscience at Singularity University
.
Singularity University
Singularity University is an academic institution in Silicon Valley whose stated aim is to "assemble, educate and inspire a cadre of leaders who strive to understand and facilitate the development of exponentially advancing technologies and apply, focus and guide these tools to address humanity’s...
where he is also executive director for the FutureMed executive program.
Daniel is the founder of StemCor Systems and founder and consulting chief medical officer for RegenMed Systems, a clinical-stage medical device company that develops tools to enable regenerative stem cell therapies. He is the inventor of the MarrowMiner, a minimally invasive device for the harvest of bone marrow derived stem and progenitor cells. This device is being commercialized by Hospira Inc. for use in bone marrow transplantation and by RegenMed Systems for use in regenerative medicine.
Dr. Kraft received a degree in Biochemistry from Brown University
Brown University
Brown University is a private, Ivy League university located in Providence, Rhode Island, United States. Founded in 1764 prior to American independence from the British Empire as the College in the English Colony of Rhode Island and Providence Plantations early in the reign of King George III ,...
and his M.D. from the Stanford University School of Medicine
Stanford University School of Medicine
Stanford University School of Medicine is a leading medical school located at Stanford University Medical Center in Stanford, California. Originally based in San Francisco, California as Cooper Medical College, it is the oldest continuously running medical school in the western United States...
. He completed the Harvard combined residency in Internal Medicine and Pediatrics at the Massachusetts General Hospital
Massachusetts General Hospital
Massachusetts General Hospital is a teaching hospital and biomedical research facility in the West End neighborhood of Boston, Massachusetts...
and the Boston Children's Hospital, before returning to Stanford for clinical fellowship training in hematology/oncology and bone marrow transplantation and a post-doctoral fellowship with Dr. Irving Weissman
Irving Weissman
Irving Lerner "Irv" Weissman M.D. is a Professor of Pathology and Developmental Biology at Stanford University where he is the Director of the Stanford Institute of Stem Cell Biology and Regenerative Medicine....
. Dr. Kraft is board certified in both Pediatrics and Internal Medicine.
In addition to his research and scientific papers, Dr. Kraft has spoken publicly on, performed research into, and consulted on: health data, health statistics, personalized medicine, heath decision making, the future of medicine, and emerging medical technologies.
Research Profile
As part of his early research at the National Institutes of Health, Dr. Kraft conceived of and demonstrated proof of concept for a monoclonal antibody-based therapy for treating allergic disease; his general approach was later translated to an antibody Xolair therapeutic by GenentechGenentech
Genentech Inc., or Genetic Engineering Technology, Inc., is a biotechnology corporation, founded in 1976 by venture capitalist Robert A. Swanson and biochemist Dr. Herbert Boyer. Trailing the founding of Cetus by five years, it was an important step in the evolution of the biotechnology industry...
. As a Howard Hughes Medical Institute
Howard Hughes Medical Institute
Howard Hughes Medical Institute is a United States non-profit medical research organization based in Chevy Chase, Maryland. It was founded by the American businessman Howard Hughes in 1953. It is one of the largest private funding organizations for biological and medical research in the United...
medical student research fellow at Stanford, he discovered at novel population of developing T-cells, which play a role in HIV infection. His research focuses extensively on stem cell biology, immunology, and regenerative medicine.
Dr. Kraft's research focuses on: stem cell biology and regenerative medicine, stem cell derived immunotherapies for cancer, bioengineering, the hematopoietic stem cell niche in murine and human systems, human T-cell differentiation, and humanized animal models. Dr. Kraft's clinical work focuses on: bone marrow / hematopoietic Stem cell transplantation for malignant and non-malignant diseases in adults & children, medical devices to enable stem cell based regenerative medicine, including marrow derived stem cell harvesting, processing and delivery.
Dr. Kraft built the first Internet-based alphanumeric paging system at the Stanford hospitals to facilitate communication between clinical staff, and later for elements of Stanford internal medicine and bone marrow transplant service.
In addition to his research at and in connection with Stanford University, Dr. Kraft has performed research into and consulting on health data, health statistics, personalized medicine and heath decision making, including work as an adviser to CollabRx (personalized oncology), Wellsphere (health and wellness) (acquired by HealthCentral
HealthCentral
HealthCentral is a privately owned online health company that was founded by an emergency room doctor in 1999. HealthCentral was later acquired by a group of venture investors in 2005. Initial investments were made from Polaris Venture Partners, Sequoia Capital, The Carlyle Group, and Allen &...
), Cepheid (point of care diagnostics), and to the X-Prize Foundation.
Scientific Papers
Daniel Kraft has scientific publications to his credit, including several in ScienceScience (journal)
Science is the academic journal of the American Association for the Advancement of Science and is one of the world's top scientific journals....
and Nature
Nature (journal)
Nature, first published on 4 November 1869, is ranked the world's most cited interdisciplinary scientific journal by the Science Edition of the 2010 Journal Citation Reports...
. He has lectured extensively on stem cell biology and regenerative medicine, and has authored several book chapters.
Publications include the following articles: Endochondral ossification is required for haematopoietic stem-cell niche formation, Scientific Paper: Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches, Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction, Efficacy of a Novel, Minimally Invasive Bone Marrow Harvesting Device in Pre-Clinical Evaluation and First Human Use, Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction, Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease, Hematopoietic Stem Cells- Basic Science and Clinical Applications, Detection and characterization of cellular immune responses using peptide-MHC microarrays, Venoconstrictive thigh cuffs impede fluid shifts during simulated microgravity, HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo, Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate, and Inhibition of allergic reactions with monoclonal antibody to the high affinity IgE receptor.
Aerospace Medicine
Dr. Kraft has research and clinical expertise in aerospace medicine.He is a Major in the Air National Guard
Air National Guard
The Air National Guard , often referred to as the Air Guard, is the air force militia organized by each of the fifty U.S. states, the commonwealth of Puerto Rico, the territories of Guam and the U.S. Virgin Islands, and the District of Columbia of the United States. Established under Title 10 and...
and serves as flight surgeon, originally with an F-15
F-15 Eagle
The McDonnell Douglas F-15 Eagle is a twin-engine, all-weather tactical fighter designed by McDonnell Douglas to gain and maintain air superiority in aerial combat. It is considered among the most successful modern fighters with over 100 aerial combat victories with no losses in dogfights...
squadron in the Massachusetts Air National Guard
Massachusetts Air National Guard
The Massachusetts Air National Guard is the air force militia of the U.S. state of Massachusetts. It is, along with the Massachusetts Army National Guard, an element of the Massachusetts National Guard...
and currently with an F-16 squadron in the 144th Fighter Wing
144th Fighter Wing
The United States Air Force's 144th Fighter Wing is a unit of the California Air National Guard, operationally gained by the Air Combat Command and located at Fresno Air National Guard Base / Fresno Yosemite International Airport in Fresno, California....
, California Air National Guard
California Air National Guard
The California Air National Guard is the air component of the California National Guard. The California Air National Guard is headquartered at Sacramento, California.One of the duties of the California Air National Guard is defense of the United States...
, with whom he has deployed to Nicaragua
Nicaragua
Nicaragua is the largest country in the Central American American isthmus, bordered by Honduras to the north and Costa Rica to the south. The country is situated between 11 and 14 degrees north of the Equator in the Northern Hemisphere, which places it entirely within the tropics. The Pacific Ocean...
and Saudi Arabia
Saudi Arabia
The Kingdom of Saudi Arabia , commonly known in British English as Saudi Arabia and in Arabic as as-Sa‘ūdiyyah , is the largest state in Western Asia by land area, constituting the bulk of the Arabian Peninsula, and the second-largest in the Arab World...
.
Dr. Kraft is a graduate of the International Space University
International Space University
The International Space University is a private university founded in 1987. The University currently offers three degree granting programs — Master of Science in Space Management, Master of Science in Space Studies and Executive MBA — in addition to a non-degree-granting Space Studies Program.The...
. Additionally, he has published physiological research at NASA-Ames
NASA Ames Research Center
The Ames Research Center , is one of the United States of America's National Aeronautics and Space Administration 10 major field centers.The centre is located in Moffett Field in California's Silicon Valley, near the high-tech companies, entrepreneurial ventures, universities, and other...
and JSC
Lyndon B. Johnson Space Center
The Lyndon B. Johnson Space Center is the National Aeronautics and Space Administration's center for human spaceflight training, research and flight control. The center consists of a complex of 100 buildings constructed on 1,620 acres in Houston, Texas, USA...
, and was a finalist for astronaut selection.
Public Talks
Dr. Kraft has presented talks at a number of venues which have been recorded and are available online including two TEDTalks. Dr. Kraft's talks include presentations at the TEDTED (conference)
TED is a global set of conferences owned by the private non-profit Sapling Foundation, formed to disseminate "ideas worth spreading"....
and 2009 & 2011 TEDMED conferences, Singularity University, the Web 2.0 summit, and the 2009 Keynote Address at the USC Body Computing Conference.
Talks and panel discussions include: "TEDTalk - Medicine's Future", "Hype, Hope & Reality in Stem Cells and Regenerative Medicine", "The Future of Medicine", "The Future of Health", and "The Convergence of Life Sciences, Medicine and Exponentially Advancing Life Technologies." and a TED presentation on the Marrow Miner, a minimally invasive bone marrow and adult stem cell harvesting device invented by Dr. Kraft.
Advisory Positions
- Adviser to the X Prize FoundationX Prize FoundationThe X PRIZE Foundation is a non-profit organization that designs and manages public competitions intended to encourage technological development that could benefit mankind....
(Life Sciences) - Adviser to CollabRx (Personalized Oncology)
- Adviser to Wellsphere (general health and wellness)
- Adviser to Cepheid (point of care diagnostics)
- Adviser to Lunar DesignLunar DesignLUNAR is a product design and development consultancy based in the San Francisco Bay Area.- History :LUNAR was founded in 1984 by Jeff Smith, Gerard Furbershaw and Robert Brunner. Capabilities include product and package design, engineering, strategic design, interaction design, and medical...
Other Appointments
While a resident at Harvard, Dr. Kraft founded, developed, and operated the Online Medical Bookstore (later acquired by Netivation), one of the first online marketplaces for medical students and professionals.Dr. Kraft is a founder of StemCor Systems.
Dr. Kraft serves as faculty track chair for Medicine & Neuroscience at Singularity University
Singularity University
Singularity University is an academic institution in Silicon Valley whose stated aim is to "assemble, educate and inspire a cadre of leaders who strive to understand and facilitate the development of exponentially advancing technologies and apply, focus and guide these tools to address humanity’s...
.
Honors
- Adaptive Business Leaders 2011 "Leadership in Innovation" Awardee & Keynote speaker:
- Young Investigator Award, American Society for Bone Marrow Transplantation (ASBMT) (2008)
- Research Award, Hope Street Kids Foundation (2006)
- Clinical Scientist Developmental Award (K-08), NHLBI/NIH (2005)
- Astronaut selection finalist (Mission Specialist), NASA (2004)
- National Innovation grant: Collegiate Inventors and Innovators Alliance, NCIIA (2003)
- United States Air Force Meritorious Achievement Medal (2000)
- Research Fellowship, Pediatric Scientist Development Program (PSDP)
- Innovation Grant, National Collegiate Inventors & Innovators Alliance (NCIIA)
- Dean's Award for Research, Stanford Medical School
- HHMI Research Training Fellowship, Howard Hughes Medical Institute