David Flavell
Encyclopedia
Dr David J Flavell BSc
PhD
FRCPath is a British academic research scientist specialising in the development of antibody-based treatments for adults and children with various forms of leukaemia and lymphoma.
Born in Southport, Lancashire in 1953, he obtained his Bachelor’s degree in applied Biology from Liverpool in 1975 and his PhD in cancer immunology from Sheffield in 1978. He has held posts at the University of Sheffield
(1975–78), Mahidol University
, Bangkok, Thailand (1978–79), The University of London, London School of Hygiene and Tropical Medicine (1979–1983) and the University of Southampton
Medical School (1984–2005). He became a member of the The Royal Society of Pathologists in 1997 and later a Fellow of the same Royal Society in 2004.
David Flavell co-founded the children’s leukaemia research charity Leukaemia Busters together with his wife Dr Sopsamorn (Bee) Flavell, Robert and Wendy Sutcliffe and Julie Daws. Shortly after the formation of Leukaemia Busters in 1989 he became the charity’s honorary Scientific Director and remained so until 2005 when he retired from his post as Senior Lecturer at the University of Southampton to become full time Scientific Director for the charity. He has retained an honorary title with the University of Southampton Medical School.
David Flavell’s career in cancer research spans more than 35 years and during this time he has made significant research contributions in a number of areas, most notably the development of a particular class of antibody-based drug termed immunotoxins that are capable of targeting cancer cells in the patients’ body without harming normal tissues. He has been largely responsible for three separate early phase clinical trials with immunotoxins in adult patients with B-cell non-Hodgkin’s lymphoma (B-NHL), multiple myeloma
and in children with pre-B cell acute lymphoblastic leukaemia (ALL).
David Flavell also heads The Simon Flavell Leukaemia Research Laboratory
at Southampton General Hospital
, so named after his ten year old son who died with T-cell acute lymphoblastic leukaemia in 1990. The main thrust of his current research is concerned with the development of the next generation of genetically engineered immunotoxins and devising ways of improving their therapeutic effectiveness and widening their therapeutic window.
Over the years David Flavell has published many original research papers in high ranking international medical journals and as chapters in various academic book titles. He continues to collaborate with scientists in Italy, Germany, Thailand and the USA in pursuit of his research objective of devising improved treatments for patients with currently incurable forms of leukaemia and lymphoma
David Flavell has been married to Dr Sopsamorn (Bee) Flavell since 1978 with whom he has worked in medical research almost continuously since 1975. They have two daughters and live in Hampshire.
BSC
BSC is a three-letter abbreviation that may refer to:Science and technology* Bachelor of Science , an undergraduate degree* Base Station Controller, part of a mobile phone network; see: Base Station subsystem...
PhD
PHD
PHD may refer to:*Ph.D., a doctorate of philosophy*Ph.D. , a 1980s British group*PHD finger, a protein sequence*PHD Mountain Software, an outdoor clothing and equipment company*PhD Docbook renderer, an XML renderer...
FRCPath is a British academic research scientist specialising in the development of antibody-based treatments for adults and children with various forms of leukaemia and lymphoma.
Born in Southport, Lancashire in 1953, he obtained his Bachelor’s degree in applied Biology from Liverpool in 1975 and his PhD in cancer immunology from Sheffield in 1978. He has held posts at the University of Sheffield
University of Sheffield
The University of Sheffield is a research university based in the city of Sheffield in South Yorkshire, England. It is one of the original 'red brick' universities and is a member of the Russell Group of leading research intensive universities...
(1975–78), Mahidol University
Mahidol University
Mahidol University is a public research university in Bangkok, Thailand. Established back in 1888 as School of Medical Practitioners, Siriraj Hospital and reorganized in 1943 as University of Medical Sciences . The university originally focused on Health Sciences but also expanded to other...
, Bangkok, Thailand (1978–79), The University of London, London School of Hygiene and Tropical Medicine (1979–1983) and the University of Southampton
University of Southampton
The University of Southampton is a British public university located in the city of Southampton, England, a member of the Russell Group. The origins of the university can be dated back to the founding of the Hartley Institution in 1862 by Henry Robertson Hartley. In 1902, the Institution developed...
Medical School (1984–2005). He became a member of the The Royal Society of Pathologists in 1997 and later a Fellow of the same Royal Society in 2004.
David Flavell co-founded the children’s leukaemia research charity Leukaemia Busters together with his wife Dr Sopsamorn (Bee) Flavell, Robert and Wendy Sutcliffe and Julie Daws. Shortly after the formation of Leukaemia Busters in 1989 he became the charity’s honorary Scientific Director and remained so until 2005 when he retired from his post as Senior Lecturer at the University of Southampton to become full time Scientific Director for the charity. He has retained an honorary title with the University of Southampton Medical School.
David Flavell’s career in cancer research spans more than 35 years and during this time he has made significant research contributions in a number of areas, most notably the development of a particular class of antibody-based drug termed immunotoxins that are capable of targeting cancer cells in the patients’ body without harming normal tissues. He has been largely responsible for three separate early phase clinical trials with immunotoxins in adult patients with B-cell non-Hodgkin’s lymphoma (B-NHL), multiple myeloma
Multiple myeloma
Multiple myeloma , also known as plasma cell myeloma or Kahler's disease , is a cancer of plasma cells, a type of white blood cell normally responsible for the production of antibodies...
and in children with pre-B cell acute lymphoblastic leukaemia (ALL).
David Flavell also heads The Simon Flavell Leukaemia Research Laboratory
The Simon Flavell Leukaemia Research Laboratory
The Simon Flavell Leukaemia Research Laboratory is based at Southampton General Hospital and named after ten year old Simon Flavell who died in 1990 from an aggressive form of T-cell acute lymphoblastic leukaemia...
at Southampton General Hospital
Southampton General Hospital
Southampton General Hospital is a large Teaching Hospital in Southampton, England, operated by University Hospital Southampton NHS Foundation Trust...
, so named after his ten year old son who died with T-cell acute lymphoblastic leukaemia in 1990. The main thrust of his current research is concerned with the development of the next generation of genetically engineered immunotoxins and devising ways of improving their therapeutic effectiveness and widening their therapeutic window.
Over the years David Flavell has published many original research papers in high ranking international medical journals and as chapters in various academic book titles. He continues to collaborate with scientists in Italy, Germany, Thailand and the USA in pursuit of his research objective of devising improved treatments for patients with currently incurable forms of leukaemia and lymphoma
David Flavell has been married to Dr Sopsamorn (Bee) Flavell since 1978 with whom he has worked in medical research almost continuously since 1975. They have two daughters and live in Hampshire.